Recombinant microorganism having ability to produce poly(lactate-coglycolate) or copolymer thereof from xylose and method for preparing poly(lactate-coglycolate) or copolymer thereof by using same
First Claim
1. A recombinant microorganism having the ability to produce poly(lactate-co-glycolate), wherein a polyhydroxyalkanoate synthase-encoding gene, a propionyl-CoA transferase-encoding gene, a xylose dehydrogenase-encoding gene, and a xylonolactonase-encoding gene are introduced in a microorganism having the ability to produce lactate from pyruvic acid, wherein the recombinant microorganism has an ability to produce poly(lactate-co-glycolate) without supplying glycolate.
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Abstract
The present invention relates to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers from xylose, and more particularly to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers without having to supply a glycolate precursor from an external source, and a method of producing a poly(lactate-co-glycolate) copolymers using the same.
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Citations
14 Claims
- 1. A recombinant microorganism having the ability to produce poly(lactate-co-glycolate), wherein a polyhydroxyalkanoate synthase-encoding gene, a propionyl-CoA transferase-encoding gene, a xylose dehydrogenase-encoding gene, and a xylonolactonase-encoding gene are introduced in a microorganism having the ability to produce lactate from pyruvic acid, wherein the recombinant microorganism has an ability to produce poly(lactate-co-glycolate) without supplying glycolate.
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