Methods for complete blood count measurement
First Claim
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1. A device for analyzing blood cells in a sample, comprising:
- a cartridge device, wherein the cartridge device comprises;
a fluidic conduit configured for receiving the sample into the cartridge device;
a chamber fluidly connected to the fluidic conduit and configured for mixing at least a portion of the sample with at least of a portion of a reagent to form one or more sample mixtures; and
a flow cell fluidly connected to the chamber and configured for forming one or more sample streams from the one or more sample mixtures without a sheath flow; and
a reader instrument device configured for receiving the cartridge device, measuring one or a plurality of signals from the sample streams in the flow cell, and analyzing the blood cells in the sample.
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Abstract
The disclosure relates to devices and methods for analyzing blood cells in a sample. In various embodiments, the present disclosure provides devices and methods of performing complete blood count (CBC) testing. In various embodiments, the present disclosure provides a cartridge device and a reader instrument device, wherein the reader instrument device receives, operates, and/or actuates the cartridge device. In various embodiments, the present disclosure provides a method of using a device as disclosed herein for analyzing blood cells in a sample.
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Citations
35 Claims
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1. A device for analyzing blood cells in a sample, comprising:
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a cartridge device, wherein the cartridge device comprises; a fluidic conduit configured for receiving the sample into the cartridge device; a chamber fluidly connected to the fluidic conduit and configured for mixing at least a portion of the sample with at least of a portion of a reagent to form one or more sample mixtures; and a flow cell fluidly connected to the chamber and configured for forming one or more sample streams from the one or more sample mixtures without a sheath flow; and a reader instrument device configured for receiving the cartridge device, measuring one or a plurality of signals from the sample streams in the flow cell, and analyzing the blood cells in the sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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Specification