Micro powered ultra-high resolution electromagnetic sensor with real time analog circuitry based artifact cancellation

• US 10,641,734 B2
• Filed: 08/27/2017
• Issued: 05/05/2020
• Est. Priority Date: 08/28/2016
• Status: Active Grant

• Current Assignee: Xtrava, Inc.
• Original Assignee: Xtrava, Inc.
• Inventors: Sarhan, Sameh, Zuckerman, Lawrence Herbert
• Primary Examiner(s): Olson, Jason C
• Application Number:
  US15/687,478
• Publication Number:
  US 20180059059A1
• Time in Patent Office: 982 Days
• Field of Search: 324243
• CPC Class Codes: A61B 2562/0223 Magnetic field sensors
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/242 Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
• CPC Class Codes: A61B 5/6804 Garments; Clothes
• CPC Class Codes: A61B 5/7214 using signal cancellation, e.g. based on input of two identical physiological sensors spaced apart, or based on two signals derived from the same sensor, for different optical wavelengths
• CPC Class Codes: G01N 27/72 by investigating magnetic variables

Abstract

An ultra-miniature and micro-powered system, apparatus, and method utilizing electromagnetic imaging via minute eddy currents, analog circuit averaging and artifact cancellation, that attaches to the outside of clothing and measures internal bodily functions including but not limited to heart rate, respiration rate, and wetness of underclothing.

Claims

1. An electromagnetic imaging instrument to measure internal properties and movement of a target object within a container or body, where there is also a spurious relative motion of the instrument and the container or body, the instrument comprising:

an eddy current measuring apparatus that outputs a composite signal containing information about said internal properties and movement of the target object contaminated with information about the spurious relative motion;

an auxiliary motion sensing means driving an auxiliary motion sensing means processing circuitry having an auxiliary motion sensing means processing circuitry output signal that contains only information about the spurious relative motion; and

a difference measuring circuit to output a signal that subtracts a value of one signal from another, wherein, the composite signal is fed to a first input of the difference measuring circuit and the auxiliary motion sensing means processing circuitry output signal is fed to a second input of the difference measuring circuit, and

a signal processing means, wherein the signal processing means output contains less contamination from information about the spurious relative motion than the composite signal.

2. The system of claim 1, wherein:

the auxiliary motion sensing means processing circuitry includes filtering to obtain spectral components of the spurious relative motion.

3. The system of claim 1:

where the relative motion of the instrument and the container or body signal is caused by accelerating motion of the instrument, the auxiliary motion sensing means processing circuitry comprising;

an accelerometer, measuring an instantaneous acceleration of the instrument, driving a 1st time integrator circuit to provide a velocity signal from the accelerometer, driving a 2nd time integrator circuit to provide a position signal from the 1st time integrator circuit, a means to initialize said integrator circuits whenever the instrument is touching the surface of the container or body, and additional accelerometer and integrator processing circuitry, where the 2nd time integrator circuit and the composite signal each feed an input of a difference amplifier input whereby the difference amplifier output contains less contamination from information about the spurious relative motion than the composite signal.

4. The system of claim 1:

where the eddy current measuring apparatus is comprised of a frequency agile monochromatic carrier generator coupled to a passive parallel tuned circuit probe containing a coil inductor and capacitors, wherein the probe has a quality factor (Q) value range from 50 to 500,

means to measure and adjust the generator frequency, wherein the frequency range comprises a resonant frequency of the parallel tuned circuit and offsets to the resonant frequency, wherein the offsets comprise a range designed to measure loaded Q values of the probe, an AM detector configured to measure and adjust the generator output level, means to measure a phase difference between an input and output of the parallel tuned circuit, means to measure the output level of the parallel resonant circuit, and a feedback loop circuitry, comprising a phase detector and a loop filter, to maintain the output level of the parallel tuned circuit constant, regardless of the target object'"'"'s eddy current loss, wherein the eddy current sensing apparatus output signal comes from the parallel tuned circuit input, as a measurement of the target object'"'"'s eddy current loss.

5. The system of claim 4, wherein:

the feedback loop circuitry output level and the input level of the parallel tuned circuit are frozen at a point within the measurement range of the eddy current measurement apparatus, whereby the output level of the parallel tuned circuit will vary in accordance with incremental eddy current losses of the target object.

6. The system of claim 4, wherein:

the auxiliary motion sensing means is comprised of an auxiliary eddy current measurement apparatus identical to the eddy current measurement apparatus, except that a coil inductor of the auxiliary eddy current measurement apparatus'"'"' parallel tuned circuit is sufficiently small that eddy currents are induced only at the proximal surface of the container or body, whereby an output signal contains information only about spurious relative motion of the instrument and the container or body.

7. The system of claim 4:

wherein;

the auxiliary motion sensing means processing circuitry includes a means to switch the resonant frequency of the eddy current measurement apparatus back and forth between a higher frequency and a lower frequency, where operation of the eddy current measurement apparatus at the higher frequency permits eddy current penetration to the target object enabling the eddy current measurement apparatus to deliver the composite signal, and

operation at the lower frequency permits eddy currents only at the proximal surface of the container or body, whereby the eddy current measurement apparatus output signal contains information only about the spurious relative motion of the instrument and the container or body, where a sample and hold circuit causes the reading from the eddy current measurement apparatus at one frequency to exist while said apparatus is operating at the other frequency; and

subtraction of the spurious relative motion signal from the composite signal occurs in the different measuring circuit.

8. The system of claim 4, wherein:

the auxiliary motion sensing means processing circuitry includes a means to switch the parallel resonant circuit of the eddy current measurement apparatus back and forth between a higher power level and a lower power level, where operation of the parallel resonant circuit at the higher power permits eddy current penetration to the target object enabling the eddy current measurement apparatus to deliver the composite signal, and operation parallel resonant circuit at the lower power level permits eddy currents only at the proximal surface of the container or body, so that the eddy current measurement apparatus output signal contains information only about the spurious relative motion of the instrument and the container or body;

a sample and hold circuit causes the reading from the eddy current measurement apparatus at one parallel resonant circuit power level to exist while said apparatus is operating at the other power level; and

subtraction of the spurious relative motion signal from the composite signal occurs in the difference measuring circuit.

9. An electromagnetic imaging eddy current instrument to measure internal properties and movement of a target object within a container or body, where there is also a spurious relative motion of the instrument and the container or body, the instrument comprising:

an oscillator whose tank circuit consists of a parallel tuned circuit that includes a coil inductor also functioning as an eddy current probe, where the parallel tuned circuit is connected to an input of a buffer amplifier, an output of a voltage-to-current converter, a fixed bias current source and an auxiliary variable bias current source driven by a sensor means that measures the spurious relative motion of the instrument and the container or body;

where the buffer amplifier feeds a signal input of a gain-controlled amplifier, which in turn feeds an input of the voltage-to-current converter;

where the parallel tuned circuit, the buffer amplifier, the gain-controlled amplifier, and the voltage-to-current converter constitute the oscillator, where the buffer amplifier also feeds an amplitude demodulator which in turn feeds a signal input of a servo integrator;

where the servo amplifier, through a cascaded sample and hold circuit in the sample mode and a low pass filter complete a closed control loop by feeding a control input of the gain-controlled amplifier;

whereby the closed control loop maintains the oscillator output and the amplitude demodulator output at a constant level over a wide range of losses reflected to the parallel tuned circuit by the target object and container or body, as corrected for the spurious relative motion of the instrument and the container or body by the auxiliary variable bias current source, causing the servo integrator output level to represent only the loss reflected to the parallel tuned circuit by the target object; and

where a closed control loop mode output of the instrument is the servo integrator output.

10. The system of claim 9, where at a chosen level within the eddy current instrument measurement range, a control means connected to a control input of the sample and hold circuit switches the sample and hold circuit to the hold mode, causing the gain of the gain-controlled amplifier to be frozen to create an open loop mode;

whereby the amplitude demodulator output level varies in accordance with incremental eddy current losses of the target object, and where an open loop mode output of the instrument is the amplitude demodulator output.

11. The system of claim 10, where:

during operation of the closed control loop mode, the oscillator output and the buffer amplifier signal output are maintained by a setting of a reference input of the servo integrator at a higher level than that the minimum necessary to sustain oscillation of the oscillator;

whereby when in open loop mode, the amplitude demodulator output level has an expanded and closer to linear measurement range of the eddy current loss.

12. The system of claim 9 wherein:

the auxiliary variable bias current source is frozen;

the instrument measures a composite signal comprised of internal properties and movement of the target object within the container or body combined with that of the container or body, where there is also a spurious relative motion of the instrument and the container or body;

an auxiliary instrument, identical to the instrument except that the coil inductor of the auxiliary instrument'"'"'s parallel tuned circuit is sufficiently small that eddy currents are induced only at the proximal surface of the container or whereby the closed loop mode and open loop mode output signals contain information only about spurious relative motion of the instrument and the container or body;

the closed loop mode outputs of the instrument and the auxiliary instrument are connected to a set of inputs of a closed loop difference amplifier, and the open loop mode outputs of the instrument and the auxiliary instrument are connected to a set of inputs of an open loop difference amplifier;

whereby,

the output of each said difference amplifier delivers the composite signal with the spurious relative motion signal having been removed.

13. The system of claim 9, wherein:

removal of information about spurious relative motion of the instrument and the container or body employs a means to switch the resonant frequency of the instrument back and forth between a higher frequency and a lower frequency, where the auxiliary variable bias current source is frozen;

operation of the instrument at the higher frequency permits eddy current penetration to the target object enabling the instrument to deliver the composite signal, and operation at the lower frequency permits eddy currents only at the proximal surface of the container or body, so that the instrument output signal contains information only about the spurious relative motion of the instrument and the container or body, a sample and hold circuit causes the reading from the eddy current measurement apparatus at one frequency to exist while said apparatus is operating at the other frequency; and

subtraction of the spurious relative motion signal from the composite signal occurs in a difference measuring circuit, whereby the instrument closed loop and open loop output signals contain information only about the internal properties and movement of a target object.

14. The system of claim 9, wherein:

removal of information about spurious relative motion of the instrument and the container or body employs a means to switch the parallel resonant circuit of the instrument back and forth between a higher power level and a lower power level, where the auxiliary variable bias current source is frozen, operation of the parallel resonant circuit at the higher power permits eddy current penetration to the target object enabling the instrument to deliver the composite signal, and operation of the parallel resonant circuit at the lower power level permits eddy currents only at the proximal surface of the container or body, enabling the instrument to deliver the signal containing information about only about the spurious relative motion of the instrument and the container or body, a sample and hold circuit causes the reading from the eddy current measurement apparatus at one parallel resonant circuit power level to exist while the instrument is operating at the other power level; and

subtraction of the spurious relative motion signal from the composite signal occurs in a difference measuring circuit, thereby leaving only information about the target object.

15. The system of claim 9:

where the relative motion of the instrument and the container or body signal is caused mainly by accelerating motion of the instrument, the circuitry to provide the auxiliary current source with the relative motion of the instrument and the container or body signal, comprising an accelerometer, measuring an instantaneous acceleration of the instrument, driving a 1st time integrator circuit to provide a velocity signal from the accelerometer, driving a 2nd time integrator circuit to provide a position signal from the 1st time integrator circuit, and a means to initialize said integrator circuits whenever the instrument is touching the surface of the container or body, and additional accelerometer and integrator processing circuitry, where the 2nd time integrator feeds the auxiliary current source with the relative motion signal.