×

Sample injection with fluidic connection between fluid drive unit and sample accommodation volume

  • US 10,641,746 B2
  • Filed: 05/30/2017
  • Issued: 05/05/2020
  • Est. Priority Date: 05/30/2016
  • Status: Active Grant
First Claim
Patent Images

1. An injector for injecting a fluidic sample into a main flow path between a fluid drive and a separation unit of a sample separation apparatus, the injector comprising:

  • a sample accommodation volume configured to accommodate the fluidic sample prior to injecting;

    a sample drive configured to intake the fluidic sample into the sample accommodation volume, and to drive the intaken fluidic sample along a metering flow path from the sample accommodation volume to the main flow path;

    a fluidic valve switchable between multiple switching states to thereby selectively couple the sample accommodation volume with the main flow path or decouple the sample accommodation volume from the main flow path, wherein in an injection switching state of the fluidic valve, the fluid drive, the separation unit and the sample drive are fluidically coupled by the fluidic valve so that the intaken fluidic sample, driven by the sample drive and flowing from the sample accommodation volume to the separation unit along the metering flow path, and further fluid driven by the fluid drive and flowing from the fluid drive to the separation unit along the main path are combined at a fluidic connection upstream of the separation unit; and

    a control unit configured to control a pressure during injecting the fluidic sample from the sample accommodation volume into the main flow path, the pressure selected from the group consisting of;

    the pressure of the intaken fluidic sample driven by the sample drive;

    the pressure of the further fluid driven by the fluid drive; and

    the pressure of the combined fluid as the combination of the intaken fluidic sample driven by the sample drive and the further fluid driven by the fluid drive.

View all claims
  • 2 Assignments
Timeline View
Assignment View
    ×
    ×