Dialysis system and disposable set

• US 10,646,634 B2
• Filed: 09/25/2018
• Issued: 05/12/2020
• Est. Priority Date: 07/09/2008
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Yu, Alex Anping, Grayson, James, Childers, Robert W.
• Primary Examiner(s): Drodge, Joseph W
• Application Number:
  US16/141,353
• Publication Number:
  US 20190076591A1
• Time in Patent Office: 595 Days
• Field of Search: 210 85, 210 86, 210 91, 210 962, 210143, 2103216, 210645-647, 604 401, 604 501, 604 601, 604 609, 604 29, 604 65- 67, 604131, 706 45- 47
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1603 Regulation parameters
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 1/341 by measuring the filtrate rate or volume
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3327 Measuring
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/3576 with non implanted data transmission devices, e.g. using external transmitter or receiver
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: B01D 61/30 : Accessories; Auxiliary operation
• CPC Class Codes: B01D 61/32 : Controlling or regulating
• CPC Class Codes: G16H 20/40 : relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture

Abstract

An example peritoneal dialysis system is disclosed. The example peritoneal dialysis system includes an automated peritoneal dialysis (“APD”) machine comprising a pumping mechanism and a peritoneal dialysis fluid heater. The example peritoneal dialysis system also includes a disposable set comprising a disposable cassette operable with the pumping mechanism and a heater bag operable with the heater. The example peritoneal dialysis system additionally includes a conductivity sensor positioned and arranged to provide feedback to the APD machine. The example APD machine is configured to mix a peritoneal dialysis fluid for treatment in the heater bag using a plurality of peritoneal dialysis constituent fluids. In addition, the example APD machine is configured to use feedback from the conductivity sensor to evaluate the mixed peritoneal dialysis fluid for treatment.

Claims

1. A peritoneal dialysis system comprising:

an automated peritoneal dialysis (“

APD”

) machine including a pumping mechanism, a logic implementer, and a peritoneal dialysis fluid heater; and

a disposable set including

a disposable cassette operable with the pumping mechanism and a heater bag operable with the heater for mixing peritoneal dialysis fluid, and

a conductivity sensor located so as to sense conductivity of the peritoneal dialysis fluid mixed in the heater bag and to provide feedback to the APD machine, wherein the APD machine is configured to mix the peritoneal dialysis fluid for treatment in the heater bag using a plurality of peritoneal dialysis constituent fluids,

wherein the logic implementer is configured to control the mixing of the peritoneal dialysis fluid to achieve a specified concentration while the peritoneal dialysis fluid is heated in the heater bag, receive the feedback from the conductivity sensor, and use the feedback to ensure that the pumping mechanism has pumped the plurality of peritoneal dialysis constituent fluids into the heater bag for mixing the peritoneal dialysis fluid so as to achieve the specified concentration.

2. The peritoneal dialysis system of claim 1, wherein the conductivity sensor is fitted with the heater bag.

3. The peritoneal dialysis system of claim 1, wherein feedback from the conductivity sensor is temperature compensated.

4. The peritoneal dialysis system of claim 1, wherein the peritoneal dialysis constituent fluids include a dextrose supply.

5. The peritoneal dialysis system of claim 1, wherein the peritoneal dialysis constituent fluids include a plurality of different dextrose supplies.

6. The peritoneal dialysis system of claim 5, wherein the logic implementer is configured to use the feedback to control the pumping mechanism to pump the different dextrose supplies so as to achieve the specified concentration.

7. The peritoneal dialysis system of claim 1, wherein the feedback from the conductivity sensor changes as a dextrose level of the mixed peritoneal dialysis fluid for treatment changes.

8. The peritoneal dialysis system of claim 1, wherein the dialysis machine includes a heater tray positioned and arranged to receive the heater bag.

9. The peritoneal dialysis system of claim 1, wherein the pumping mechanism is a pneumatic pumping mechanism.

10. The peritoneal dialysis system of claim 1, wherein the pumping mechanism is an electromechanical pumping mechanism.

11. A peritoneal dialysis system comprising:

an automated peritoneal dialysis (“

APD”

) machine including a pumping mechanism, a logic implementer, and a peritoneal dialysis fluid heater;

a disposable set including

a dextrose supply,

a disposable cassette in fluid communication with the dextrose supply and operable with the pumping mechanism, and

a heater bag operable with the heater for mixing peritoneal dialysis fluid; and

a conductivity sensor located so as to sense conductivity of the peritoneal dialysis fluid mixed in the heater bag and to provide feedback to the APD machine, wherein the APD machine is configured to mix the peritoneal dialysis fluid for treatment in the heater bag using a constituent fluid from the dextrose supply,

wherein the logic implementer is configured to control the mixing of the peritoneal dialysis fluid to achieve a specified concentration while the peritoneal dialysis fluid is heated in the heater bag, receive the feedback from the conductivity sensor, and use the feedback to ensure that the pumping mechanism has pumped the constituent fluid into the heater bag for mixing the peritoneal dialysis fluid so as to achieve the specified concentration.

12. The peritoneal dialysis system of claim 11, wherein the conductivity sensor is fitted with the heater bag.

13. The peritoneal dialysis system of claim 11, wherein the dextrose supply is in fluid communication with the disposable cassette via a first supply tube of the disposable set, and which includes a second constituent fluid supply in fluid communication with the disposable cassette via a second supply tube of the disposable set.

14. The peritoneal dialysis system of claim 13, wherein the APD machine is configured to operate valve chambers of the disposable set to control fluid entering the cassette via the first and second supply tubes.

15. The peritoneal dialysis system of claim 13, wherein the APD machine is configured to pump fluid into the disposable set through the first and second supply tubes at a specified ratio.

16. The peritoneal dialysis system of claim 11, wherein the mixed peritoneal dialysis fluid for treatment has a blended dextrose level between 1.5% and 4.25%.

17. A peritoneal dialysis system comprising:

an automated peritoneal dialysis (“

APD”

) machine including a pumping mechanism, and a logic implementer;

a disposable set including

a dextrose supply,

a disposable cassette in fluid communication with the dextrose supply and operable with the pumping mechanism, and

a mixing container operable for mixing and heating peritoneal dialysis fluid; and

a conductivity sensor located so as to sense conductivity of the peritoneal dialysis fluid mixed in the mixing container and configured to provide feedback to the APD machine, wherein the APD machine is configured to mix the peritoneal dialysis fluid for treatment in the mixing container using a constituent fluid from the dextrose supply,

wherein the logic implementer is configured to control the mixing of the peritoneal dialysis fluid to achieve a specified concentration while the peritoneal dialysis fluid is heated, receive the feedback from the conductivity sensor, and use the feedback to ensure that the pumping mechanism has pumped the constituent fluid into the mixing container for mixing the peritoneal dialysis fluid so as to achieve the specified concentration.

18. The peritoneal dialysis system of claim 17, wherein the disposable cassette includes a plurality of valve chambers, and wherein the logic implementer causes the valve chambers to operate using feedback from the conductivity sensor to control dextrose fluid from the dextrose supply to form the mixed fluid for treatment.

19. The peritoneal dialysis system of claim 17, wherein the dialysis machine includes a heater, and wherein the mixing container is a heater bag operable with the heater.