Talbot-lau x-ray source and interferometric system

• US 10,656,105 B2
• Filed: 07/29/2019
• Issued: 05/19/2020
• Est. Priority Date: 08/06/2018
• Status: Active Grant

• Current Assignee: Sigray, Inc
• Original Assignee: Sigray, Inc
• Inventors: Yun, Wenbing, Lewis, Sylvia Jia Yun, Kirz, Janos, Vine, David
• Primary Examiner(s): Song, Hoon K
• Application Number:
  US16/525,198
• Publication Number:
  US 20200041428A1
• Time in Patent Office: 295 Days
• Field of Search: None
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/4007 characterised by using a plurality of source units
• CPC Class Codes: A61B 6/4035 the source being combined with a filter or grating
• CPC Class Codes: A61B 6/4291 the detector being combined with a grid or grating
• CPC Class Codes: A61B 6/484 involving phase contrast X-ray imaging
• CPC Class Codes: G01N 2223/204 source created from radiated target
• CPC Class Codes: G01N 23/02 by transmitting the radiation through the material
• CPC Class Codes: G01N 23/20075 by measuring interferences of X-rays, e.g. Borrmann effect
• CPC Class Codes: G21K 2207/005 Methods and devices obtaining contrast from non-absorbing interaction of the radiation with matter, e.g. phase contrast
• CPC Class Codes: H01J 2235/086 Target geometry
• CPC Class Codes: H01J 35/08 Anodes; Anti cathodes

Abstract

An x-ray source and an x-ray interferometry system utilizing the x-ray source are provided. The x-ray source includes a target that includes a substrate and a plurality of structures. The substrate includes a thermally conductive first material and a first surface. The plurality of structures is on or embedded in at least a portion of the first surface. The structures are separate from one another and are in thermal communication with the substrate. The structures include at least one second material different from the first material, the at least one second material configured to generate x-rays upon irradiation by electrons having energies in an energy range of 0.5 keV to 160 keV. The x-ray source further includes an electron source configured to generate the electrons and to direct the electrons to impinge the target and to irradiate at least some of the structures along a direction that is at a non-zero angle relative to a surface normal of the portion of the first surface. The x-ray source further includes at least one optical element positioned such that at least some of the x-rays are transmitted through the first material and to or through the at least one optical element.

Claims

1. An x-ray source comprising:

a target comprising;

a substrate comprising a thermally conductive first material and a first surface; and

a plurality of structures on or embedded in at least a portion of the first surface, the structures separate from one another and in thermal communication with the substrate, the structures comprising at least one second material different from the first material, the at least one second material configured to generate x-rays upon irradiation by electrons having energies in an energy range of 0.5 keV to 160 keV; and

an electron source configured to generate the electrons and to direct the electrons to impinge the target and irradiate at least some of the structures along a direction that is at a non-zero angle relative to a surface normal of the portion of the first surface, the angle and a kinetic energy of the electrons configured such that at least some of the electrons have an electron penetration depth within the target sufficient to penetrate the first surface and irradiate at least two of the structures.

2. The x-ray source of claim 1, further comprising an x-ray window comprising the target, at least some of the x-rays transmitted through the first material and through a second surface of the target.

3. The x-ray source of claim 1, wherein the angle is greater than 20 degrees.

4. The x-ray source of claim 1, wherein the angle is in a range of 40 degrees to 85 degrees.

5. The x-ray source of claim 1, wherein the angle is in a range of 40 degrees to 60 degrees.

6. The x-ray source of claim 1, wherein the angle equals 60 degrees.

7. The x-ray source claim 1, wherein energy deposition from the electrons to the structures is greater than energy deposition from the electrons to the substrate.

8. The x-ray source of claim 1, wherein the substrate comprises a second surface that is opposite and generally parallel to the first surface, and the substrate has a thickness between the first surface and the second surface in a range of 250 microns to 3000 microns.

9. The x-ray source of claim 8, wherein the structures extend from the first surface towards the second surface to a depth in a range of 1 micron to 30 microns.

10. The x-ray source of claim 8, wherein the structures extend from the first surface towards the second surface to a depth in a range of 2 microns to 10 microns.

11. The x-ray source of claim 8, wherein the x-rays are transmitted through the second surface of the substrate to the at least one optical element.

12. The x-ray source of claim 1, wherein at least some of the structures each extend along the first surface in at least one lateral direction by a width in a range of 0.5 micron to 5 microns.

13. The x-ray source of claim 1, wherein at least some of the structures are separate from one another along the first surface by a separation distance greater than 0.3 micron.

14. The x-ray source of claim 13, wherein the separation distance is in a range of 1 micron to 2 microns.

15. The x-ray source of claim 1, wherein the first material comprises at least one of:

diamond, silicon carbide, beryllium, and sapphire.

16. The x-ray source of claim 1, wherein the first material has a thermal conductivity in a range between 20 W/m-K and 2500 W/m-K and comprises elements with atomic numbers less than or equal to 14.

17. The x-ray source of claim 1, wherein the at least one second material comprises at least one of:

tungsten, gold, and molybdenum.

18. The x-ray source of claim 1, wherein the target further comprises at least one interface layer between the first material and the at least one second material, the at least one interface layer comprising at least one third material different from the first material and the at least one second material.

19. The x-ray source of claim 18, wherein the at least one third material comprises at least one of:

titanium nitride, iridium, and hafnium oxide.

20. The x-ray source of claim 1, wherein the target further comprises at least one layer overlaying the structures at the first surface.

21. The x-ray source of claim 20, wherein the at least one layer is electrically conductive and/or seals the structures between the at least one layer and the substrate.

22. The x-ray source of claim 20, wherein the at least one layer comprises the first material.

23. The x-ray source of claim 1, wherein the x-rays are in an energy range of 2 keV to 85 keV.

24. The x-ray source of claim 1, wherein the x-rays are emitted from the target in a beam comprising a plurality of sub-beams each propagating from a corresponding one of the plurality of structures.

25. The x-ray source of claim 1, further comprising at least one optical element positioned such that at least some of the x-rays are transmitted through the first material and to or through the at least one optical element, wherein the at least one optical element comprises a solid material that is substantially transparent to the at least some of the x-rays.

26. An x-ray interferometry system comprising:

an x-ray source comprising;

a target comprising;

a substrate comprising a thermally conductive first material and a first surface; and

a plurality of structures on or embedded in at least a portion of the first surface, the structures separate from one another and in thermal communication with the substrate, the structures comprising at least one second material different from the first material, the at least one second material configured to generate x-rays upon irradiation by electrons having energies in an energy range of 0.5 keV to 160 keV; and

an electron source configured to generate the electrons and to direct the electrons to impinge the target and irradiate at least some of the structures along a direction that is at a non-zero angle relative to a surface normal of the portion of the first surface, the angle and a kinetic energy of the electrons configured such that at least some of the electrons have an electron penetration depth within the target sufficient to penetrate the first surface and irradiate at least two of the structures.

27. The x-ray interferometry system of claim 26, having a Talbot-Lau interferometry configuration.

28. The x-ray interferometry system of claim 27, comprising a Talbot x-ray microscope.