Methods of removing heat from an electrode using thermal shunting

• US 10,660,701 B2
• Filed: 09/28/2018
• Issued: 05/26/2020
• Est. Priority Date: 11/19/2014
• Status: Active Grant

• Current Assignee: EPIX Therapeutics, Inc. (Medtronic Plc)
• Original Assignee: EPIX Therapeutics, Inc. (Medtronic Plc)
• Inventors: Schultheis, Eric Andrew, Koblish, Josef Vincent, Panescu, Dorin
• Primary Examiner(s): Fowler, Daniel W
• Application Number:
  US16/147,403
• Publication Number:
  US 20190029753A1
• Time in Patent Office: 606 Days
• CPC Class Codes: A61B 18/1206 Generators therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00023 closed, i.e. without wound contact by the fluid
• CPC Class Codes: A61B 2018/00029 open
• CPC Class Codes: A61B 2018/00083 low, i.e. electrically insulating
• CPC Class Codes: A61B 2018/00101 low, i.e. thermally insulating
• CPC Class Codes: A61B 2018/0016 Energy applicators arranged in a two- or three dimensional array
• CPC Class Codes: A61B 2018/00351 Heart
• CPC Class Codes: A61B 2018/00357 Endocardium
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00672 lower
• CPC Class Codes: A61B 2018/00678 upper
• CPC Class Codes: A61B 2018/00702 Power or energy
• CPC Class Codes: A61B 2018/00714 Temperature
• CPC Class Codes: A61B 2018/00761 Duration
• CPC Class Codes: A61B 2018/00797 measured by multiple temperature sensors
• CPC Class Codes: A61B 2018/00815 measured by a thermistor
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG
• CPC Class Codes: A61B 2018/00875 : Resistance or impedance
• CPC Class Codes: A61B 2018/128 : generating two or more frequencies
• CPC Class Codes: A61B 2018/1467 : using more than two electrodes on a single probe
• CPC Class Codes: A61B 2217/007 : with irrigation system
• CPC Class Codes: A61B 2218/002 : Irrigation
• CPC Class Codes: A61B 2562/046 : in a matrix array
• CPC Class Codes: A61B 5/01 : Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/068 : using impedance sensors
• CPC Class Codes: A61B 5/150954 : Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/287 : Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
• CPC Class Codes: A61B 5/6852 : Catheters

Abstract

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Claims

1. A method of heat removal from an electrode assembly during a tissue treatment procedure, the method comprising:

delivering energy to an electrode assembly of an ablation system, the ablation system comprising a catheter comprising a distal end, the electrode assembly positioned along the distal end of the catheter;

the catheter of the ablation system comprises a plurality of thermal shunt members along its distal end,

a first one of the plurality of thermal shunt members extends at least partially through an interior of the electrode assembly;

a second one of the plurality of thermal shunt members being disposed proximal to the first one of the plurality of thermal shunt members, a third one of the plurality of shunt members being distal to and spaced apart from the second one of the plurality of shunt members by at least a portion of the electrode assembly, the second one and the first one of the plurality of thermal shunt members being differently sized;

the catheter further comprises at least one fluid passage extending at least partially through the interior of the electrode assembly and an interior of the plurality of thermal shunt members;

delivering a fluid through the at least one fluid passage; and

transferring heat from the electrode assembly to the fluid via the plurality of thermal shunt members to reduce the likelihood of localized hot spots along the distal end of the catheter.

2. The method of claim 1,

wherein the plurality of thermal shunt members is configured to transfer heat while not retaining heat, and wherein the plurality of thermal shunt members comprises a thermal diffusivity greater than 1.5 cm²/sec;

wherein the electrode assembly comprises at least one radiofrequency electrode; and

wherein the at least one fluid passage is configured to place the electrode assembly in fluid communication with a fluid source to selectively remove heat from the electrode assembly and/or tissue of a subject located adjacent the electrode assembly.

3. The method of claim 1, wherein the plurality of thermal shunt members is configured to transfer heat while not retaining heat, and wherein the plurality of thermal shunt members comprises a thermal diffusivity greater than 1.5 cm²/sec.

4. The method of claim 1, wherein the plurality of thermal shunt members comprises a diamond or other carbon-based material.

5. The method of claim 1, wherein the electrode assembly comprises a composite electrode, the composite electrode comprising a first electrode portion and at least a second electrode portion, wherein an electrically insulating gap is located between the first electrode portion and the at least a second electrode portion to facilitate high-resolution mapping along a targeted anatomical area.

6. The method of claim 1, wherein the at least one fluid passage is configured to place the electrode assembly in fluid communication with a fluid source to selectively remove heat from the electrode assembly and tissue of a subject located adjacent the electrode assembly.

7. The method of claim 1, wherein the at least one fluid passage is in direct thermal communication with plurality of thermal shunt members.

8. The method of claim 1, wherein the at least one fluid passage comprises at least one opening, wherein the at least one opening allows fluid flowing through the at least one fluid passage to exit the catheter.

9. A method of heat removal from an electrode assembly during a tissue treatment procedure, comprising:

delivering energy to an electrode assembly of an ablation system, the electrode assembly positioned along a distal end of an elongate body;

a plurality of thermal shunt members extends at least partially through an interior of the electrode assembly, the plurality of thermal shunt members further includes a first thermal shunt member spaced from a second thermal shunt member, the second thermal shunt member being differently sized that the first thermal shunt member;

a third one of the plurality of shunt members being distal to and spaced apart from the second one of the plurality of shunt members by at least a portion of the electrode assembly; and

the elongate body further comprises at least one fluid passage extending at least partially through the interior of the plurality of thermal shunt members

delivering a fluid through the at least one fluid passage; and

transferring heat from the electrode assembly to the fluid via the plurality of thermal shunt members to reduce the likelihood of localized hot spots along the distal end of the elongate body.

10. The method of claim 9,

wherein the at least one thermal shunt member is configured to transfer heat while not retaining heat, and wherein the at least one thermal shunt member comprises a thermal diffusivity greater than 1.5 cm²/sec;

and

wherein the at least one fluid passage is configured to place the electrode assembly in fluid communication with a fluid source to selectively remove heat from the electrode assembly and/or tissue of a subject located adjacent the electrode assembly.

11. The method of claim 9, wherein the plurality of thermal shunt members is configured to transfer heat while not retaining heat, and wherein the at least one thermal shunt member comprises a thermal diffusivity greater than 1.5 cm²/sec.

12. The method of claim 9, wherein the plurality of thermal shunt members comprises a diamond or other carbon-based material.

13. The method of claim 9, wherein the electrode assembly comprises a composite electrode, the composite electrode comprising a first electrode portion and at least a second electrode portion, wherein an electrically insulating gap is located between the first electrode portion and the at least a second electrode portion to facilitate high-resolution mapping along a targeted anatomical area.

14. The method of claim 9, wherein the at least one fluid passage is in direct thermal communication with the plurality of thermal shunt members.

15. A method of heat removal from an ablation member during a tissue treatment procedure, comprising:

delivering energy to an ablation member of an ablation system, the ablation member positioned along a distal end of an elongate body;

a plurality of thermal shunt members extends at least partially through an interior of the ablation member; and

at least one fluid passage extends at least partially through an interior of the plurality of thermal shunt members, the plurality of thermal shunt members further includes a first thermal shunt member spaced from a second thermal shunt member, at least a portion of the ablation member being disposed between the first and second thermal shunt members, the second thermal shunt member being differently sized that the first thermal shunt member, a third one of the plurality of thermal shunt members being differently sized than first thermal shunt member and the second thermal shunt member;

delivering a fluid through the at least one fluid passage; and

transferring heat from the electrode assembly to the fluid via the plurality of thermal shunt members.

16. The method of claim 15,

wherein the plurality of thermal shunt members is configured to transfer heat while not retaining heat, and wherein the plurality of thermal shunt members comprises a thermal diffusivity greater than 1.5 cm²/sec;

and

wherein the at least one fluid passage is configured to place the ablation member in fluid communication with a fluid source to selectively remove heat from the ablation member and tissue of a subject located adjacent the ablation member.

17. The method of claim 15, wherein the plurality of thermal shunt members is configured to transfer heat while not retaining heat, and wherein plurality of thermal shunt members comprises a thermal diffusivity greater than 1.5 cm²/sec.

18. The method of claim 15, wherein the plurality of thermal shunt members comprises a diamond or other carbon-based material.

19. The method of claim 15, wherein the ablation member comprises a composite electrode, the composite electrode comprising a first electrode portion and at least a second electrode portion, wherein an electrically insulating gap is located between the first electrode portion and the at least a second electrode portion to facilitate high-resolution mapping along a targeted anatomical area.

20. The method of claim 15, wherein the at least one fluid passage is in direct thermal communication with the plurality of thermal shunt members.