Modular point-of-care devices, systems, and uses thereof
First Claim
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1. A method of measuring a volume of a liquid sample, comprising:
- reacting a known quantity of a control analyte in the liquid sample with a reagent to yield a detectable signal indicative of the quantity of the control analyte; and
comparing the detectable signal indicative of the quantity of the control analyte with an expected signal,wherein the expected signal is indicative of an expected volume of the liquid sample, andwherein the comparison provides a measurement of the volume of the liquid sample being measured.
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Abstract
The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.
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Citations
17 Claims
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1. A method of measuring a volume of a liquid sample, comprising:
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reacting a known quantity of a control analyte in the liquid sample with a reagent to yield a detectable signal indicative of the quantity of the control analyte; and comparing the detectable signal indicative of the quantity of the control analyte with an expected signal, wherein the expected signal is indicative of an expected volume of the liquid sample, and wherein the comparison provides a measurement of the volume of the liquid sample being measured. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of measuring a volume of a liquid sample using a bench-top, point-of-care system including an assay assembly, a fluid transfer device, and a detection assembly, the method comprising:
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reacting a known quantity of a control analyte in the liquid sample with a reagent to yield a detectable signal indicative of the quantity of the control analyte; and comparing the detectable signal indicative of the quantity of the control analyte with an expected signal, wherein the expected signal is indicative of an expected volume of the liquid sample; and determining the volume of the liquid sample based on comparing the expected signal and the detectable signal. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17)
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Specification