Hydrophilic polymer coatings with durable lubricity and compositions and methods thereof

• US 10,687,976 B1
• Filed: 02/05/2020
• Issued: 06/23/2020
• Est. Priority Date: 10/14/2016
• Status: Active Grant

• Current Assignee: Hydroglyde Coatings LLC
• Original Assignee: Hydroglyde Coatings LLC
• Inventors: Chin, Stacy Lee, Cooper, Benjamin Goldman, Xiao, Ruiqing, Grinstaff, Mark W.
• Primary Examiner(s): Mulcahy, Peter D.
• Application Number:
  US16/782,262
• Publication Number:
  US 20200170830A1
• Time in Patent Office: 139 Days
• CPC Class Codes: A61F 6/04 Condoms, sheaths or the like , e.g. combined with devices protecting against contagion
• CPC Class Codes: B29C 41/22 Making multilayered or multicoloured articles
• CPC Class Codes: B32B 2307/728 Hydrophilic
• CPC Class Codes: B32B 27/26 using curing agents
• CPC Class Codes: B32B 27/28 comprising synthetic resins not wholly covered by any one of the sub-groups B32B27/30 - B32B27/42
• CPC Class Codes: B32B 27/285 comprising polyethers
• CPC Class Codes: B32B 27/30 comprising vinyl (co)polymers; comprising acrylic (co)polymers
• CPC Class Codes: B32B 27/302 comprising aromatic vinyl (co)polymers, e.g. styrenic (co)polymers
• CPC Class Codes: B32B 27/306 comprising vinyl acetate or vinyl alcohol (co)polymers
• CPC Class Codes: B32B 27/36 comprising polyesters
• CPC Class Codes: C08J 2300/26 Elastomers
• CPC Class Codes: C08J 2307/00 Characterised by the use of natural rubber
• CPC Class Codes: C08J 2307/02 Latex
• CPC Class Codes: C08J 2347/00 Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, at least one having two or more carbon-to-carbon double bonds; Derivatives of such polymers C08J2345/00 takes precedence; of conjugated diene rubbers C08J2309/00 - C08J2321/00
• CPC Class Codes: C08J 2407/02 Latex
• CPC Class Codes: C08J 2409/02 Copolymers with acrylonitrile
• CPC Class Codes: C08J 7/042 with two or more layers, where at least one layer of a composition contains a polymer binder
• CPC Class Codes: C08J 7/043 Improving the adhesiveness of the coatings per se, e.g. forming primers adhesives in the form of films or foils characterised by the primer layers between the polymer carriers and the adhesives C09J7/50
• CPC Class Codes: C08J 7/056 Forming hydrophilic coatings
• CPC Class Codes: C08L 11/02 Latex
• CPC Class Codes: C08L 29/04 : Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
• CPC Class Codes: C08L 7/02 : Latex
• CPC Class Codes: C08L 9/08 : Latex
• CPC Class Codes: C09D 107/02 : Latex
• CPC Class Codes: C09D 109/08 : Latex

Abstract

The invention provides a novel hydrophilic polymer and latex polymer blend coating formulation and compositions thereof, and their use on various devices (e.g., prophylactic and medical devices) to form hydrophilic and flexible coatings with durable lubricity.

Claims

1. A method for manufacturing a condom, comprising:

providing a sheath of an elastomeric material selected from natural or synthetic rubber latex, the sheath having an outer surface and an inner surface;

depositing a first layer of an aqueous suspension of a latex polymer to at least a portion of the outer surface of the sheath;

curing the latex polymer with exposure to heat for a time sufficient to form a first or base layer of cured latex polymer;

depositing a second layer of a composition, comprising a hydrophilic polymer and a suspension of latex polymer, to at least a portion of the first or base layer; and

curing the second layer of hydrophilic polymer and latex polymer with exposure to heat for a time sufficient to form a second or top layer,

wherein

the hydrophilic polymer has a mean molecular weight in the range from about 1 kDa to about 1,000 kDa and is present in the composition at a concentration from about 2 w/v % to about 10 w/v %;

the latex polymer microparticles are present in the composition at a concentration from about 20 w/v % to about 60 w/v %; and

the weight ratio of the hydrophilic polymer to the latex polymer microparticles is in the range from about 1;

1 to about 10;

1.

2. The method of claim 1, further comprising:

depositing a third or top layer of a composition, comprising a hydrophilic polymer and a suspension of latex polymer, to at least a portion of the second layer; and

curing the third layer of hydrophilic polymer and latex polymer with exposure to heat for a time sufficient to form a third or top layer.

3. The method of claim 1, wherein at least a portion of the outer surface, the first or base layer, or the second layer, is substantially all of the outer surface, the first or base layer or the second layer, respectively.

4. The method of claim 1, wherein curing the latex polymer is conducted at a temperature between about 25°

C. to about 70°

C. for a time period from about 5 to about 60 minutes.

5. The method of claim 1, wherein curing the hydrophilic polymer and a suspension of latex polymer is conducted at a temperature between about 25°

C. to about 70°

C. for a time period from about 5 to about 60 minutes.

6. The method of claim 1, wherein the first or base layer has a thickness in the range from about 0.01 mm to about 1.0 mm.

7. The method of claim 1, wherein the first or base layer has a thickness less than about 1.0 mm.

8. The method of claim 6, wherein the second, or the third if present, or top layer has a thickness in the range from about 0.01 mm to about 1.0 mm.

9. The method of claim 6, wherein the second, or the third if present, or top layer has a thickness less than about 1.0 mm.