Automated drug preparation apparatus including automated drug reconstitution

• US 10,688,021 B2
• Filed: 06/24/2019
• Issued: 06/23/2020
• Est. Priority Date: 12/03/2002
• Status: Active Grant

• Current Assignee: Baxter Corporation Englewood (Baxter International Inc.)
• Original Assignee: Baxter Corporation Englewood (Baxter International Inc.)
• Inventors: Tribble, Dennis, Osborne, Joel A., Khan, Abdul Wahid, Lefebre, Edward J.
• Primary Examiner(s): Maust, Timothy L
• Application Number:
  US16/449,990
• Publication Number:
  US 20190307643A1
• Time in Patent Office: 365 Days
• Field of Search: 141 1, 141 83, 141 94, 141192, 700216
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/20 Arrangements for transferring or mixing fluids, e.g. from vial to syringe
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61J 2200/74 for weight
• CPC Class Codes: A61J 2205/10 Bar codes
• CPC Class Codes: A61J 2205/30 Printed labels
• CPC Class Codes: A61J 3/002 Compounding apparatus specially for enteral or parenteral nutritive solutions bottling liquids B67C
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 5/2448 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: B65B 3/003 Filling medical containers such as ampoules, vials, syringes or the like
• CPC Class Codes: B65B 3/10 by application of pressure to material by screw-type feeders B65B3/08
• CPC Class Codes: B65B 3/26 Methods or devices for controlling the quantity of the material fed or filled
• CPC Class Codes: B65B 3/28 by weighing
• CPC Class Codes: B65B 43/46 using grippers
• CPC Class Codes: B65B 43/50 using rotary tables or turrets B65B43/46 takes precedence
• CPC Class Codes: B65B 7/2821 applying plugs or threadless stoppers for bottles or jars B67B1/04
• CPC Class Codes: B65C 3/06 Affixing labels to short rigid containers
• CPC Class Codes: B65C 3/26 Affixing labels to non-rigid containers, e.g. bottles made of polyethylene, boxes to be inflated by internal air pressure prior to labelling

Abstract

An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Claims

1. An automated system for use in the preparation of medication orders, comprising:

at least one database configured for storing;

a plurality of medication orders, and

identifying information for each of a plurality of medication sources;

a computer controller, in communication with the at least one database, wherein for preparation of each given order of the plurality of medication orders the computer controller is configured to;

access automatically the identifying information for at least one of the plurality of medication sources corresponding with a respective given order, and

compare automatically identifying information read from a corresponding selected medication source to the identifying information for the at least one of the plurality of medication sources corresponding with the respective given order;

a camera configured and arranged to obtain an image of the corresponding selected medication source; and

a label printer, in communication with the computer controller, wherein for each given order of the plurality of medication orders the label printer is operable to print a corresponding label for application to a corresponding delivery device for containing medication corresponding with the respective given order of the plurality of medication orders,

wherein for each given order of the plurality of medication orders the corresponding delivery device is one of a syringe and a bag, and

wherein each of the plurality of medication sources is one of a vial containing a medication and a bag containing a fluid medication.

2. The automated system as recited in claim 1, wherein for each given order of the plurality of medication orders the computer controller is configurable to:

identify automatically the at least one of the plurality of medication sources corresponding with the respective given order for use in preparation of the respective given order.

3. The automated system as recited in claim 1, further comprising:

a reader, in communication with the computer controller, wherein for each given order of the plurality of medication orders the reader is operable to;

read the identifying information from the corresponding selected medication source.

4. The automated system as recited in claim 3, wherein for a given order of the plurality of medication orders the automated system is operable to identify automatically whether the corresponding selected medication source is for multi-use.

5. The automated system as recited in claim 3, the reader comprising:

a bar code scanner.

6. The automated system as recited in claim 1, further comprising:

at least one scale, in communication with the computer controller, wherein for each given order of the plurality of medication orders the at least one scale is operable to;

measure a corresponding weight of the corresponding selected medication source, wherein the corresponding weight is stored in the system.

7. The automated system as recited in claim 6, wherein the at least one scale comprises:

a load cell; and

,

a platform on the load cell for placement of each selected medication source thereupon.

8. The automated system as recited in claim 1, wherein for each given order of the plurality of medication orders the corresponding label identifies the medication corresponding with the respective given order of the plurality of medication orders.

9. The automated system as recited in claim 8, further comprising:

a reader, in communication with the computer controller, wherein for each given order of the plurality of medication orders the reader is operable to;

read the corresponding label applied to the corresponding delivery device to confirm that the corresponding label properly identifies the medication corresponding with the given order of the plurality of medication orders.

10. The automated system as recited in claim 1, further comprising:

at least one scale, in communication with the computer controller, wherein for each given order of the plurality of medication orders the at least one scale is operable to;

measure a corresponding weight of the corresponding delivery device after delivery of the medication corresponding with the respective given order of the plurality of medication orders in to the corresponding delivery device.

11. The automated system as recited in claim 10, wherein for each given order of the plurality of medication orders the automated system is operable to:

compare automatically the corresponding weight of the corresponding delivery device to a corresponding stored value to determine if the weight of the corresponding delivery device is within a range of acceptable values.

12. The automated system as recited in claim 1, wherein for each given order of the plurality of medication orders the computer controller is operable to:

control automated delivery of the medication corresponding with the respective given order of the plurality of medication orders to the corresponding delivery device.

13. The automated system as recited in claim 1, further comprising:

a plurality of valves, in communication with the computer controller, wherein for a given order of the plurality of medication orders the plurality of valves are operable to;

selectively control fluid interconnection between each of a selected plurality of the plurality of medication sources and a common line in fluid communication with the corresponding delivery device.

14. The automated system as recited in claim 13, wherein for a given order of the plurality of medication orders the plurality of valves are operable to:

selectively control fluid interconnection between at least one diluent source and the common line in fluid communication with the corresponding delivery device.

15. The automated system as recited in claim 1, further comprising:

a computer display, wherein for each given order of the plurality of medication orders the computer display is operable for a user to track the corresponding drug delivery device in the system.

16. The automated system as recited in claim 1, further comprising:

an input in communication with the computer controller, wherein for each given order of the plurality of medication orders the input is operable to;

receive user input data that includes medication source information corresponding with the respective given order.

17. The automated system as recited in claim 1, the at least one database further configured for storing:

reconstitution instructions corresponding with each of a plurality of reconstitutable medications comprising the plurality of medication sources;

wherein for a given order of the plurality of medication orders the computer controller is configurable to;

access automatically the reconstitution instructions for at least one of the plurality of reconstitutable medications corresponding with the given order for use in preparation of the given order.

18. The automated system as recited in claim 1, further comprising:

a label printer, in communication with the computer controller, wherein for each given order of the plurality of medication orders the label printer is operable to;

print a corresponding label for application to a corresponding delivery device for containing medication corresponding with the respective given order of the plurality of medication orders; and

,

at least one scale, in communication with the computer controller, wherein for each given order of the plurality of medication orders the at least one scale is operable to;

measure a corresponding weight of the corresponding delivery device after delivery of the medication corresponding with the respective given order of the plurality of medication orders in to the corresponding delivery device.