Devices and systems for thrombus treatment

• US 10,695,084 B2
• Filed: 02/09/2017
• Issued: 06/30/2020
• Est. Priority Date: 08/14/2012
• Status: Active Grant

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Cully, Edward H., Friedman, Nathan L., Zacharias, Eric H.
• Primary Examiner(s): Herbermann, Erich G
• Application Number:
  US15/428,243
• Publication Number:
  US 20170150986A1
• Time in Patent Office: 1,237 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/320725 with radially expandable cutting or abrading elements A61B17/32075 takes precedence
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/22069 Immobilising; Stabilising
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/320004 abrasive
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61B 2017/320733 with a flexible cutting or scraping element, e.g. with a whip-like distal filament member
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00

Abstract

A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end. Each of the one or more tethers is attached at its first end to the body frame portion, and at its second end to a collar that couples the second end of each of the multiple tethers to the support wire. When the collar is advanced to a position substantially within a region interior of the body frame portion, a rotational actuation of the support wire causes a swiveling motion of the one or more tethers. The swiveling motion of the tethers operates to macerate a thrombus.

Claims

1. A medical treatment system, comprising:

a first support element having a longitudinal axis;

a body frame disposed about the longitudinal axis of the first support element, the body frame having a first portion and a second portion longitudinally offset from the first portion;

a first collar coupled to the first support element and positionable within the body frame; and

a first tether extending from the first portion of the body frame to the first collar such that when the first collar is positioned within the body frame, the first collar is rotatable such that the first tether sweeps through a range of motion without imparting substantial motion to the body frame,

wherein the first tether is routed from the first support element outward through the body frame and proximally toward the second portion of the body frame.

2. The system of claim 1, wherein the first support element is a support wire.

3. The system of claim 1, wherein the first collar is coupled to the first support element such that articulation of the first support element causes the first collar to articulate, thereby causing the first tether to sweep through the range of motion without imparting substantial motion to the body frame.

4. The system of claim 1, wherein the first collar is slideable relative to the first support element such that the first collar can translate along the first support element, the system further comprising one or more collar stops coupled to the first support element and configured to limit translation of the first collar along the first support element.

5. A medical device comprising:

a support element having a longitudinal axis;

a body frame disposed about the longitudinal axis of the support element, the body frame having a first portion and a second portion longitudinally offset from the first portion;

a collar coupled to the support element and positionable within the body frame; and

at least one tether extending between the first portion of the body frame and the collar such that when the collar is positioned within the body frame, the collar is rotatable such that the at least one tether sweeps through a range of motion without imparting substantial motion to the body frame,

wherein the at least one tether is configured to be routed from the support element outward through the body frame and proximally toward the second portion of the body frame.

6. The medical device of claim 5, wherein the support element is a support wire.

7. The medical device of claim 5, wherein the collar is coupled to the support element such that articulation of the support element causes the collar to articulate, thereby causing the at least one tether to sweep through the range of motion without imparting substantial motion to the body frame.

8. The medical device of claim 5, wherein the collar is slideable relative to the support element such that the collar can translate along the support element.

9. The medical device of claim 5, wherein the support element is a support tube having a lumen extending therethrough along the longitudinal axis of the support element.

10. The medical device of claim 5, wherein the at least one tether is located at least partially outside of a space defined by the body frame.

11. The medical device of claim 5, wherein the at least one tether is routed around the second portion of the body frame, the second portion being a proximal peripheral portion of the body frame.

12. The medical device of claim 11, wherein the at least one tether is configured to collapse the body frame by applying tension to the at least one tether.

13. The medical device of claim 12, wherein the body frame is longitudinally collapsible toward the support element by applying the tension to the at least one tether.

14. The medical device of claim 12, wherein the body frame is radially collapsible toward the support element by applying the tension to the at least one tether.

15. The medical device of claim 12, wherein collapsing the body frame enables the medical device to assume a low profile for recapture.

16. The medical device of claim 11, further comprising a plurality of tethers extending between the first portion of the body frame and the collar, wherein each of the plurality of tethers is attached to the body frame such that the plurality of tethers cooperatively form a single loop around the proximal peripheral portion of the body frame.

17. A medical device comprising:

a support tube having a longitudinal axis, a lumen extending therethrough along the longitudinal axis, and a distal end;

a body frame disposed about the longitudinal axis of the support tube, the body frame having a first portion and a second portion longitudinally offset from the first portion; and

at least one tether extending between the first portion of the body frame and the distal end of the support tube such that when the distal end of the support tube is positioned within the body frame, the support tube is rotatable such that the at least one tether sweeps through a range of motion without imparting substantial motion to the body frame,

wherein the at least one tether exits the support tube proximate to the distal end and is routed approximately radially outward through the body frame proximate to the first portion of the body frame and routed proximally toward the second portion of the body frame, wherein the at least one tether is located at least partially outside of a space defined by the body frame.

18. The medical device of claim 17, wherein the at least one tether is routed around the second portion of the body frame, the second portion being a proximal peripheral portion of the body frame.

19. The medical device of claim 18, wherein the at least one tether is configured to collapse the body frame by applying tension to the at least one tether.

20. The medical device of claim 19, wherein the body frame is inwardly collapsible toward the support tube by applying the tension to the at least one tether.

21. The medical device of claim 18, further comprising a plurality of tethers extending between the first portion of the body frame, wherein each of the plurality of tethers is attached to the body frame such that the plurality of tethers cooperatively form a single loop around the proximal peripheral portion of the body frame.

22. The medical device of claim 21, wherein collapsing the body frame enables the medical device to assume a low profile for recapture.