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Nanoelectroablation control and vaccination

  • US 10,695,127 B2
  • Filed: 04/15/2019
  • Issued: 06/30/2020
  • Est. Priority Date: 12/01/2014
  • Status: Active Grant
First Claim
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1. A method of vaccinating a subject against a tumor, the method comprisingpassing multiple treatments of sub-microsecond pulsed electric fields with different parameters through tumor cells of a first subject;

  • selecting, based on the multiple treatments, optimized parameters to formulate an effective sub-microsecond pulsed electric fields treatment which increases or maximizes apoptosis of the tumor cells of the first subject; and

    using the formulated sub-microsecond pulsed electric fields treatment with the optimized parameters to create a vaccine with the increased or maximized apoptotic tumor cells to treat the tumor cells or other tumor cells of the first subject or a different subject with a same type of tumor cells.

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