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Non-cleavable polymer conjugated with alpha V beta 3 integrin thyroid antagonists

  • US 10,695,436 B2
  • Filed: 12/18/2018
  • Issued: 06/30/2020
  • Est. Priority Date: 06/07/2016
  • Status: Active Grant
First Claim
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1. A method of synthesizing a composition, the method comprising:

  • conjugating a non-biodegradable polymer to a thyroid antagonist using a linker;

    wherein the linker is covalently bound to the thyroid antagonist and the non-biodegradable polymer via a non-cleavable bond,wherein the linker comprises one of the following;

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