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Alpha-hydroxy carboxylic acid and derivatives and other GRAS based prodrugs of oxycodone and uses thereof

  • US 10,696,683 B2
  • Filed: 05/30/2018
  • Issued: 06/30/2020
  • Est. Priority Date: 04/27/2015
  • Status: Active Grant
First Claim
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1. An oxycodone prodrug of the following formula where the prodrug moiety X is attached covalently to the oxycodone molecule via the 6 position ketone enolate oxygen as the enolate ester,

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