Neurostimulation device

• US 10,702,692 B2
• Filed: 03/02/2018
• Issued: 07/07/2020
• Est. Priority Date: 03/02/2018
• Status: Active Grant

• Current Assignee: Aleva Neurotherapeutics
• Original Assignee: Aleva Neurotherapeutics
• Inventors: Mercanzini, Andre, Struzka, Zbynek, Ruan, Jason Jinyu, Harbi, Pascal, Jordan, Alain
• Primary Examiner(s): Stice, Paula J
• Application Number:
  US15/910,278
• Publication Number:
  US 20190269906A1
• Time in Patent Office: 858 Days
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0539 Anchoring of brain electrode systems, e.g. within burr hole
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system

Abstract

The present disclosure describes an implantable lead device that includes an internal support comb. The support comb can include one or more faces that enable the alignment, routing, and holding of the lead device'"'"'s internal wires. The support comb can enable the interconnection of the wires with to the microelectrode film that includes the lead device'"'"'s electrodes.

Claims

1. An implantable lead device, comprising:

a support comb comprising;

an attachment face; and

a routing face comprising a plurality of slots;

a microelectrode film comprising a body having a plurality of electrodes and an extension comprising;

a first leg, the first leg of the extension having a plurality of electrical contacts coupled with the plurality of electrodes; and

a second leg, the second leg of the extension coupled with the attachment face of the support comb; and

a plurality of wires, each of the plurality of wires passing through a respective one of the plurality of slots and coupled with a respective one of the plurality of electrical contacts.

2. The lead of claim 1, wherein the attachment face comprises a channel to route an adhesive under at least a portion of the second leg of the microelectrode film.

3. The lead of claim 1, comprising:

a support tube; and

a face of the body of the microelectrode film coupled with the support tube.

4. The lead of claim 3, wherein the support tube comprises a plurality of radio opaque markers aligned with the plurality of electrodes.

5. The lead of claim 3, wherein the support tube comprises a plurality of merlons on a first end, the first end configured to mate with the support comb.

6. The lead of claim 1, comprising:

a support tube comprising a plurality of radio opaque markers.

7. The lead of claim 1, wherein each of the plurality of wires are coupled with the respective one of the plurality of electrical contacts with wire bonding.

8. The lead of claim 1, wherein the extension of the microelectrode film comprises:

the first leg comprising the first face of the extension and the second face of the extension; and

the second leg comprising a plurality of traces coupling a subset of the plurality of electrodes to the plurality of electrical contacts.

9. The lead of claim 1, wherein the extension of the microelectrode film comprises:

the first leg and the second leg rolled around the support comb.

10. The lead of claim 1, comprising:

an epoxy backfilling the microelectrode film.

11. A method, comprising:

providing a support comb of an implantable lead device, the support comb comprising;

an attachment face; and

a routing face comprising a plurality of slots;

coupling a first leg of a microelectrode film of the implantable lead device with the attachment face of the support comb, the first leg of the microelectrode film comprising a plurality of electrical contacts;

positioning each of a plurality of wires through a respective one of the plurality of slots of the routing face;

coupling each of the plurality of wires with a respective one of the plurality of electrical contacts; and

rolling a second leg of the microelectrode film about the support comb.

12. The method of claim 11, comprising:

forming the second leg of the microelectrode film comprising a plurality of electrodes in electrical communication with the plurality of electrical contacts; and

forming a third leg of the microelectrode film comprising a plurality of electrical traces coupling a portion of the plurality of electrodes to a portion of the plurality of electrical contacts.

13. The method of claim 11, comprising:

coupling a second leg of the microelectrode film to an outer face of a support tube, the second leg of the microelectrode film comprising the plurality of electrodes; and

filling the support tube with an epoxy.

14. The method of claim 11, comprising:

forming a plurality of radio opaque markers in a support tube; and

aligning the plurality of radio opaque markers with the plurality of electrodes formed in the microelectrode film.

15. The method of claim 11, comprising:

wire bonding each of the plurality of wires with the respective one of the plurality of electrical contacts.

16. The method of claim 11, comprising:

rolling the second leg of the microelectrode film to form a cylinder; and

filling the cylinder with an epoxy.

17. The method of claim 11, comprising:

underfilling a channel formed in the attachment face with an epoxy to couple the first leg of the microelectrode film with the attachment face.

18. The method of claim 11, comprising:

etching the support comb in silicon.

19. The method of claim 11, comprising:

coupling a first edge of the microelectrode film with a second edge of the microelectrode film to form a cylinder.

20. The method of claim 11, comprising:

coupling the microelectrode film with a support tube; and

inserting a first edge and a second edge of the microelectrode film into a slot of the support tube.