System and methods for processing analyte sensor data for sensor calibration
First Claim
Patent Images
1. A glucose monitoring system comprising:
- a transcutaneous electrochemical glucose sensor comprising an in vivo portion and an ex vivo portion, wherein the transcutaneous electrochemical sensor is characterized by an in vivo sensitivity and an in vitro sensitivity, wherein the in vivo sensitivity is different from the in vitro sensitivity, and wherein the in vitro sensitivity is predictive of the in vivo sensitivity due to a relationship therebetween;
sensor electronics configured to be operably connected to the transcutaneous electrochemical glucose sensor;
a processor configured to be operably connected to the sensor electronics;
a memory configured to be operably connected to the processor, wherein the memory has stored therein information associated with the in vivo sensitivity of the transcutaneous electrochemical glucose sensor, wherein the information associated with the in vivo sensitivity is based at least in part on corrections for the difference between the in vivo sensitivity and the in vitro sensitivity of the transcutaneous electrochemical glucose sensor.
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1 Petition
Accused Products
Abstract
Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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Citations
10 Claims
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1. A glucose monitoring system comprising:
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a transcutaneous electrochemical glucose sensor comprising an in vivo portion and an ex vivo portion, wherein the transcutaneous electrochemical sensor is characterized by an in vivo sensitivity and an in vitro sensitivity, wherein the in vivo sensitivity is different from the in vitro sensitivity, and wherein the in vitro sensitivity is predictive of the in vivo sensitivity due to a relationship therebetween; sensor electronics configured to be operably connected to the transcutaneous electrochemical glucose sensor; a processor configured to be operably connected to the sensor electronics; a memory configured to be operably connected to the processor, wherein the memory has stored therein information associated with the in vivo sensitivity of the transcutaneous electrochemical glucose sensor, wherein the information associated with the in vivo sensitivity is based at least in part on corrections for the difference between the in vivo sensitivity and the in vitro sensitivity of the transcutaneous electrochemical glucose sensor. - View Dependent Claims (2, 3, 4)
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5. A method for calibrating data from a transcutaneous electrochemical glucose sensor, the method comprising:
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receiving sensor data from the transcutaneous electrochemical glucose sensor after at least a portion of the transcutaneous electrochemical glucose sensor is inserted in a host, wherein the sensor data is indicative of a glucose concentration in the host; and calibrating, using a processor, the sensor data received from the transcutaneous electrochemical glucose sensor, wherein the calibrating is based at least in part on information associated with an in vivo sensitivity of the transcutaneous electrochemical glucose sensor, wherein the information associated with the in vivo sensitivity is based at least in part on corrections for a difference between the in vivo sensitivity and an in vitro sensitivity for the transcutaneous electrochemical glucose sensor. - View Dependent Claims (6, 7, 8, 9)
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10. A method for providing calibrated glucose information based on sensor data from a transcutaneous electrochemical glucose sensor, the method comprising:
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receiving, by a processor, post-implantation sensor data from the transcutaneous electrochemical glucose sensor, wherein the sensor data is indicative of a glucose concentration in a host; receiving, by the processor, information associated with an in vivo sensitivity of the transcutaneous electrochemical glucose sensor, wherein the information associated with the in vivo sensitivity is based at least in part on corrections for a difference between the in vivo sensitivity and an in vitro sensitivity for the transcutaneous electrochemical glucose sensor; generating calibrated sensor data, using the processor, by using the information associated with the in vivo sensitivity of the transcutaneous electrochemical glucose sensor to calibrate the sensor data received from the transcutaneous electrochemical glucose sensor; and providing the calibrated sensor data to a user to facilitate monitoring a glucose level of the host.
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Specification