Electrically enhanced retrieval of material from vessel lumens
First Claim
1. A method for thrombectomy, comprising:
- disposing an interventional element adjacent to a thrombus within a blood vessel;
promoting adhesion of the thrombus to the interventional element by delivering an electrical signal to the interventional element, the electrical signal comprising a periodic waveform,wherein the waveform comprises a composite waveform including a superposition of a non-square waveform having a first peak current and a square waveform having a second peak current that is less than the first peak current,wherein a total energy delivered via the electrical signal is between 0.75-24,000 mJ, andwherein the first peak current is between 0.5-5 mA.
1 Assignment
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Accused Products
Abstract
Retrieval of material from vessel lumens can be improved by electrically enhancing attachment of the material to the removal device. The removal device can have a core assembly that includes a hypotube coupled to a first electrical terminal and a pushwire coupled to a second electrical terminal, the pushwire extending through the hypotube lumen. An insulating layer separates the hypotube and the pushwire, and an interventional element is coupled to a distal end of the pushwire. The interventional element can be disposed adjacent to a thrombus. An electrical signal is delivered to the interventional element to promote adhesion of the thrombus to the interventional element. The electrical signal can optionally be a periodic waveform, and the total energy delivered can be between 0.75-24,000 mJ and the peak current delivered via the electrical signal can be between 0.5-5 mA.
103 Citations
31 Claims
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1. A method for thrombectomy, comprising:
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disposing an interventional element adjacent to a thrombus within a blood vessel; promoting adhesion of the thrombus to the interventional element by delivering an electrical signal to the interventional element, the electrical signal comprising a periodic waveform, wherein the waveform comprises a composite waveform including a superposition of a non-square waveform having a first peak current and a square waveform having a second peak current that is less than the first peak current, wherein a total energy delivered via the electrical signal is between 0.75-24,000 mJ, and wherein the first peak current is between 0.5-5 mA. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method for thrombectomy, comprising:
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positioning an interventional element proximate to a thrombus, the interventional element in electrical communication with a power source; supplying an electrical composite waveform from the power source to the interventional element, the composite waveform comprising a combination of a first waveform having a first peak current and a second waveform having a second peak current that is less than the first peak current, wherein the second peak current is applied for a shorter duration of time than the first peak current, wherein a total charge supplied via the composite waveform is between 30-240 mC, and wherein the composite waveform is supplied for no more than 2 minutes. - View Dependent Claims (23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification