Retrieval of material from vessel lumens

• US 10,709,464 B2
• Filed: 05/12/2017
• Issued: 07/14/2020
• Est. Priority Date: 05/12/2017
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Deen, Daniel, Skillrud, Erik, Epstein, Evan
• Primary Examiner(s): Shi, Katherine M
• Assistant Examiner(s): Mendoza, Michael G
• Application Number:
  US15/594,462
• Publication Number:
  US 20180325536A1
• Time in Patent Office: 1,159 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/3435 using everted sleeves

Abstract

Devices for removing clot material from a blood vessel lumen and associated systems and methods are disclosed herein. A clot retrieving device may include, for example, an elongated shaft, a capture structure having a proximal portion and a distal portion, and a cover having a first portion coupled to the elongated shaft and a second portion extending from the first portion. The cover may have an inverted configuration in which the capture structure is at least partially ensheathed within the first portion of the cover and the second portion of the cover extends distally from the first portion. In the inverted configuration, the second portion may have (a) a first region distal to a distal terminus of the capture structure, the first region tapering radially inwardly in a distal direction, and (b) a second region extending distally and radially outwardly from the first region.

Claims

1. A clot retrieving device, comprising:

an elongated shaft having a distal region;

a capture structure having a proximal portion coupled to the distal region of the elongated shaft and a distal portion having a distal terminus; and

a cover having a first portion coupled to the distal region of the elongated shaft and a second portion extending from the first portion, the cover having a first configuration in which the second portion of the cover extends proximally from the first portion, and the cover having a second configuration in which the capture structure is at least partially ensheathed within the first portion of the cover and the second portion of the cover extends distally from the first portion, and in the second configuration the second portion has (a) a first region distal to a distal terminus of the capture structure, the first region tapering radially inwardly in a distal direction, and (b) a second region extending distally and radially outwardly from the first region.

2. The clot retrieving device of claim 1 wherein in the second configuration the second region of the second portion extends distally and circumferentially radially outwardly from the first region.

3. The clot retrieving device of claim 1 wherein, in the second configuration, the second portion of the cover has a third region extending proximally from the second region.

4. The clot retrieving device of claim 3 wherein, in the second configuration, the second portion of the cover has a fourth region that extends distally and radially outwardly from the third region, wherein the third region and the fourth region meet at a proximal folded edge.

5. The clot retrieving device of claim 1 wherein, in the second configuration, the first and second regions of the second portion together define a channel extending therethrough.

6. The clot retrieving device of claim 5 wherein, in the second configuration, the first portion of the cover defines an axially-extending cavity that is continuous with the channel of the second portion.

7. The clot retrieving device of claim 5 wherein a diameter of the channel decreases in a distal direction along the first region and increases in a distal direction along the second region.

8. The clot retrieving device of claim 1 wherein, when the cover is unconstrained in the first configuration, the cross-sectional area at the second portion of the cover is greater than the cross-sectional area at the first portion of the cover.

9. The clot retrieving device of claim 1 wherein the cover is a braid comprising a plurality of interwoven filaments.

10. The clot retrieving device of claim 9 wherein at least some of the plurality of filaments are drawn-filled tube (“

DFT”

) wires comprising a radiopaque core material surrounded by a superelastic material.

11. The clot retrieving device of claim 1 wherein the capture structure is a stent.

12. A clot retrieving device, comprising:

an elongated shaft having a distal region;

a capture structure having a proximal portion coupled to the distal region of the elongated shaft and a distal portion having a distal terminus; and

a cover coupled to the distal region of the elongated shaft, the cover having a first portion and a second portion extending from the first portion, wherein the cover has (a) a first configuration in which the second portion of the cover extends proximally from the first portion, and (b) a second configuration in which the capture structure is at least partially ensheathed within the first portion of the cover and the second portion extends distally from the first portion, and wherein, in the second configuration, the second portion has;

a neck portion distal to the capture structure, the neck portion having a cross-sectional area that decreases then increases in a distal direction,

a broad portion that curves radially outwardly and proximally from a distal region of the neck portion, and

a channel extending through the neck portion that terminates at an opening at a distal face of the cover.

13. The clot retrieving device of claim 12 wherein, in the second configuration, the broad portion of the second portion curves circumferentially radially outwardly and proximally from the distal region of the neck portion.

14. The clot retrieving device of claim 12 wherein, in the second configuration, the second portion of the cover has an inverted portion that extends distally and radially outwardly from the broad portion, wherein the broad portion and the inverted portion meet at a curved edge.

15. The clot retrieving device of claim 12 wherein, in the second configuration, a length of the neck portion and a length of the broad portion define the distal face of the cover.

16. The clot retrieving device of claim 12 wherein, in the second configuration, the broad portion surrounds and is spaced apart from at least a portion of the length of the neck portion.

17. The clot retrieving device of claim 12 wherein, in the second configuration, a cross-sectional area of the broad portion is greater than the cross-sectional area of the first portion of the cover.

18. The clot retrieving device of claim 12 wherein, when the cover is unconstrained in the first configuration, the cross-sectional area at the second portion of the cover is greater than the cross-sectional area at the first portion of the cover.

19. The clot retrieving device of claim 12 wherein in the second configuration the cover is inverted relative to the first configuration.

20. The clot retrieving device of claim 12 wherein the cover is a braid comprising a plurality of interwoven filaments.

21. A method for using a clot retrieval device to retrieve clot material from a blood vessel of a patient, the clot retrieval device including a capture structure and a cover having a first portion and a second portion, the method comprising:

expanding the clot retrieval device within the blood vessel lumen into a first configuration such that the second portion of the cover extends proximally from the first portion of the cover and the second portion of the cover contacts an interior surface of the vessel wall;

moving the capture structure proximally relative to the cover to transform the clot retrieval device from the first configuration into a second configuration in which (a) the first portion of the cover surrounds the capture structure, and (b) the second portion extends distally from the first portion, the second portion tapering radially inward distal to a distal terminus of the capture structure to a narrow region, and then curves radially outwardly from the narrow region to form a wide region; and

retaining at least a portion of the clot material within the cover and removing the clot material and clot retrieval device from the patient with the clot retrieval device in the second configuration.

22. The method of claim 21 wherein the wide region includes:

a first portion extending distally and radially outwardly from a distal terminus of the narrow region, and

a second portion extending proximally from a distal terminus of the first portion of the wide region.

23. The method of claim 22 wherein the wide region further includes a third portion extending distally and radially outwardly from a distal terminus of the wide region, wherein the second portion of the wide region and the third portion of the wide region meet at a proximal edge of the wide region.

24. The method of claim 21 wherein the clot retrieval device is constrained within a delivery sheath during delivery of the clot retrieval device to the clot material, and wherein expanding the clot retrieval device includes withdrawing the delivery sheath proximally beyond the cover.

25. The method of claim 21, further comprising inverting the first portion of the cover while the second portion of the cover remains in contact with the vessel wall.