Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm

• US 10,716,573 B2
• Filed: 01/09/2018
• Issued: 07/21/2020
• Est. Priority Date: 05/01/2008
• Status: Active Grant

• Current Assignee: Aneuclose LLC
• Original Assignee: Aneuclose LLC
• Inventors: Connor, Robert A.
• Primary Examiner(s): David, Shaun L
• Assistant Examiner(s): Lauer, Christina C
• Application Number:
  US15/865,822
• Publication Number:
  US 20180140305A1
• Time in Patent Office: 924 Days
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12163 having a string of elements connected to each other
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12181 formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 2017/00862 elastic or resilient for sutures A61B2017/0618
• CPC Class Codes: A61B 2017/00946 malleable
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2230/0004 Rounded shapes, e.g. with rounded corners
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2230/0071 spherical
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2230/0078 hyperboloidal
• CPC Class Codes: A61F 2230/008 paraboloidal

Abstract

This invention is an intrasacular aneurysm occlusion device with a proximal resilient stent which becomes wider than the aneurysm neck and a distal flexible net which is expanded by being filled with embolic members. The stent and the net work together. The stent occludes the aneurysm neck and prevents the device from slipping out. The net conforms to the walls of even an irregularly-shaped aneurysm sac and keeps the stent pressed against the inside of the aneurysm neck. This has advantages over the prior art, especially for aneurysms with irregularly-shaped sacs.

Claims

1. An intrasacular aneurysm occlusion device comprising:

a resilient wider-than-neck portion which is inserted into an aneurysm sac;

wherein the resilient wider-than-neck portion is collapsed in the aneurysm sac from a generally spherical configuration into a generally hemispherical, double-layered configuration;

wherein the resilient wider-than-neck portion in its hemispherical, double-layered configuration has a width which is larger than the diameter of the neck of the aneurysm sac; and

wherein the resilient wider-than-neck in its hemispherical, double-layered configuration has a first level of flexibility, elasticity, and/or malleability; and

a flexible sac-filling portion which is inserted into the aneurysm sac;

wherein the flexible sac-filling portion has a first configuration as it is being transported to an aneurysm sac and a second configuration after it has been expanded within the aneurysm sac;

wherein the flexible sac-filling portion is expanded from its first configuration to its second configuration by the insertion of embolic members into the flexible sac-filling portion; and

wherein the flexible sac-filling portion in its second configuration has a second level of flexibility, elasticity, and/or malleability which is greater than the first level of flexibility, elasticity, and/or malleability.

2. The device in claim 1 wherein the flexible sac-filling portion is a net or mesh.

3. The device in claim 1 wherein the resilient wider-than-neck portion further comprises an adjustable opening through which embolic members are inserted into the flexible sac-filling portion.

4. The device in claim 1 wherein embolic members are selected from the group consisting of:

microsponges, pieces of gel, pieces of foam, beads, microspheres, and embolic coils.

5. An intrasacular aneurysm occlusion device comprising:

a resilient wider-than-neck portion which is inserted into an aneurysm sac;

wherein the resilient wider-than-neck portion is collapsed in the aneurysm sac from a generally spherical configuration into a generally hemispherical, double-layered configuration by pulling on a wire or other longitudinal member which is attached to a distal end of the resilient wider-than-neck portion;

wherein the resilient wider-than-neck portion in its hemispherical, double-layered configuration has a width which is larger than the diameter of the neck of the aneurysm sac; and

wherein the resilient wider-than-neck has a first level of flexibility, elasticity, and/or malleability; and

a flexible sac-filling portion which is inserted into the aneurysm sac;

wherein the flexible sac-filling portion is expanded in the aneurysm sac by the insertion of embolic members into the flexible sac-filling portion; and

wherein the flexible sac-filling portion has a second level of flexibility, elasticity, and/or malleability which is greater than the first level of flexibility, elasticity, and/or malleability.