Apparatus for artificial kidney, quality evaluating device for dialyzing fluid and dialyzing means using the same, and fluid circuit

• US 20010005487A1
• Filed: 12/22/2000
• Published: 06/28/2001
• Est. Priority Date: 12/24/1999
• Status: Active Grant

• Current Assignee: Asahi Medical Co. Ltd. (Asahi Kasei Corporation)
• Original Assignee: Asahi Medical Co. Ltd. (Asahi Kasei Corporation)
• Inventors: Endo, Fumiaki, Motoyama, Shinji, Kamibayashi, Masato, Sawamoto, Jiro
• Granted Patent: US 6,555,058 B2
• Time in Patent Office: Days
• US Class Current: 422/45
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1609 after use, i.e. downstream of dialyser
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/0672 Nasal cannula assemblies for oxygen therapy
• CPC Class Codes: A61M 16/101 using an oxygen concentrator
• CPC Class Codes: A61M 2202/0275 Nitric oxide [NO]
• CPC Class Codes: A61M 2230/205 partial oxygen pressure (P-O2)

Abstract

An apparatus which can solve the problem of participation of NO in hypotension in dialysis, hypoxia in dialysis, and the like during artificial dialysis by continuously monitoring fluctuation in a blood gas, an ionic component, or the like in body fluid such as blood and by suppressing these diseases, and quality evaluating means of an artificial dialyzer and dialyzing fluid are provided. An apparatus for an artificial kidney comprises a measurement monitor for continuously measuring nitric oxide as a component of body fluid or liquid for treatment. Further, an apparatus for an artificial kidney comprises a measurement monitor for measuring a component of body fluid or liquid for treatment, a display means for comparing a measurement measured by the measurement monitor with a control value, and when the measurement equals the control value, displays the equality, and oxygen supplying means.

Claims

1. An apparatus for an artificial kidney comprising:

a first fluid circuit for introducing body fluid into dialyzing means;

dialyzing means for removing waste products from the body fluid; and

a second fluid circuit for- recovering the body fluid,

characterized by further comprising a measurement monitor for continuously measuring at least one component of the body fluid in said first fluid circuit and/or said second fluid circuit.

2. An apparatus for an artificial kidney as claimed in

claim 1

, wherein said at least one of component is selected from a group consisting of nitric oxide, oxygen, nitrous acid ions, and nitric acid ions.

3. An apparatus for an artificial kidney as claimed in

claim 1

, wherein at least one of said first fluid circuit, said dialyzing means, and said second fluid circuit is provided with a treatment liquid supplying device for supplying liquid for treatment.

4. An apparatus for an artificial kidney as claimed in claim 1, further comprising:

oxygen supplying means for increasing partial pressure of oxygen in arterial blood of a living body.

6. An apparatus for an artificial kidney as claimed in

claim 4

, wherein said oxygen supplying means is at least one which is selected from a group consisting of an air bubble type oxygenator, a membrane type oxygenator, an oxygen inhaler, an oxygen tent, an oxygen respiration synchronizer, and an oxygen concentrator.

7. An apparatus for an artificial kidney as claimed in

claim 1

, characterized in that said dialyzing means is a blood processor using a hollow fiber membrane, and/or said liquid for treatment is dialyzing fluid.

9. A fluid circuit usable in an apparatus for an artificial kidney as claimed in

claim 3

, characterized by comprising a measurement monitor for continuously measuring at least one component of the body fluid in said fluid circuits, and oxygen supplying means.

5. An apparatus for an artificial kidney comprising:

a first fluid circuit for introducing body fluid of a living body into dialyzing means;

dialyzing means for removing waste products from the body fluid;

a second fluid circuit for recovering and returning the body fluid to the living body; and

oxygen supplying means for increasing partial pressure of oxygen in arterial blood of the living body,

characterized by further comprising a measurement monitor for continuously measuring at least one component of the body fluid in said first fluid circuit and/or said second fluid circuit, and display means for displaying the result of comparison between a measurement value measured by said measurement monitor and a desired value.

8. A quality evaluating device for dialyzing means comprising:

a first fluid circuit for introducing body fluid into dialyzing means;

dialyzing means for removing waste products from the body fluid; and

a second fluid circuit for recovering the body fluid,

characterized by further comprising a measurement monitor for continuously measuring at least one component of the body fluid in said first fluid circuit and/or said second fluid circuit and by being capable of evaluating the quality of said dialyzing means.

10. A quality evaluating device for dialyzing fluid comprising:

a first fluid circuit for introducing body fluid into dialyzing means;

dialyzing means for removing waste products from the body fluid; and

a second fluid circuit for recovering the body fluid,

characterized by further comprising a measurement monitor for continuously measuring at least one component of the body fluid in said first fluid circuit and/or said second fluid circuit, optional oxygen supplying means, and a dialyzing fluid supplying device for supplying dialyzing fluid to said dialyzing means, and by being capable of evaluating the quality of the dialyzing fluid.

11. A circuit or a device as claimed in

claim 9

or

10

, respectively, wherein said oxygen supplying means is at least one which is selected from a group consisting of an air bubble type oxygenator, a membrane type oxygenator, an oxygen inhaler, an oxygen tent, an oxygen respiration synchronizer, and an oxygen concentrator.

14. A method as claimed in

claim 10

, wherein the oxygen supplying means is at least one which is selected from a group consisting of an air bubble type oxygenator, a membrane type oxygenator, an oxygen inhaler, an oxygen tent, an oxygen respiration synchronizer, and an oxygen concentrator.

12. A dialyzing fluid supplying device comprising:

a third fluid circuit for introducing dialyzing fluid; and

a fourth fluid circuit for recovering the dialyzing fluid,

characterized by further comprising a measurement monitor for continuously measuring at least one component of the dialyzing fluid in said third fluid circuit and/or said fourth fluid circuit.

13. A method of controlling the concentration of a component of body fluid of a living body by comprising a first fluid circuit for introducing body fluid of a living body into dialyzing means, dialyzing means for removing waste products from the body fluid, a second fluid circuit for recovering and returning the body fluid to the living body, and oxygen supplying means for increasing partial pressure of oxygen in arterial blood of the living body, by further comprising a measurement monitor for continuously measuring at least one component of the body fluid in the first fluid circuit and/or the second fluid circuit, and by comparing a measurement value measured by the measurement monitor with a desired value.

15. A dialyzing fluid supplying device comprising a third fluid circuit for introducing dialyzing fluid, and a fourth fluid circuit for recovering the dialyzing fluid, characterized by further comprising a measurement monitor for continuously measuring at least one component of the dialyzing fluid in the third fluid circuit and/or the fourth fluid circuit.