Water-soluble or water-swellable crosslinked copolymers

• US 20010029287A1
• Filed: 01/11/2001
• Published: 10/11/2001
• Est. Priority Date: 01/11/2000
• Status: Active Grant

• Current Assignee: Clariant Produkte AG (Clariant AG)
• Original Assignee: Clariant GmbH (Clariant AG)
• Inventors: Loffler, Matthias, Morschhauser, Roman
• Granted Patent: US 6,437,068 B2
• Time in Patent Office: Days
• US Class Current: 526/263
• CPC Class Codes: A61K 47/32 Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers , poly(meth)acrylates, or polyvinyl pyrrolidone
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 9/0014 Skin, i.e. galenical aspects of topical compositions non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: C08F 220/585 and containing other heteroatoms, e.g. 2-acrylamido-2-methylpropane sulfonic acid [AMPS]

Abstract

Water-soluble or water-swellable crosslinked copolymers consisting essentially of structural units of the formula 1

or a mixture of the structural units of the formula 1 with structural units of the formula 2

and structural units of the formula 3

where R, R¹, R², R³, Z and n are as defined in the description. These copolymers are crosslinked with compounds which contain at least two olefinic double bonds. These crosslinked copolymers are suitable as thickeners, in particular for cosmetic and pharmaceutical preparations.

Claims

1. A water-soluble or water-swellable crosslinked copolymer consisting essentially of

a1) 1 to 50% by weight of the repeating structural unit of the formula (1)

where n is an integer from 2 to 9, or

a2) 1 to 50% by weight of a mixture of the repeating structural unit of the formula (1) and of the repeating structural unit of the formula (2)

where R, R¹ and R² may be identical or different and are hydrogen or a linear or branched alkyl or alkenyl group having in each case 1 to 30, preferably 1 to 20, in particular 1 to 12, carbon atoms and

b) 49.99 to 98.99% by weight of the repeating structural unit of the formula (3)

in which R³ is hydrogen, methyl or ethyl, Z is C₁-C₈-alkylene, n is an integer from 2 to 9, and X is an alkali metal or alkaline earth metal ion, and

c) 0.01 to 8% by weight of crosslinking structures resulting from monomers having at least two olefinic double bonds.

2. The copolymer as claimed in

claim 1

, consisting essentially of 2 to 30% by weight of the repeating structural unit of the formula 1 or a mixture of the repeating structural units of the formulae 1 and 2, 69.5 to 97.5% by weight of the repeating structural unit of the formula 3 and 0.2 to 3% by weight of crosslinking structures resulting from monomers having at least two olefinic double bonds.

3. The copolymer as claimed in

claim 1

, consisting essentially of 3 to 15% by weight of the repeating structural unit of the formula 1 or a mixture of the repeating structural units of the formulae 1 and 2, 84.5 to 96.5% by weight of the repeating structural unit of the formula 3 and 0.5 to 2% by weight of crosslinking structures resulting from monomers having at least two olefinic double bonds.

4. The copolymer as claimed in

claim 1

, comprising crosslinking structures resulting from allyl (meth)acrylate.

5. A process for the preparation of the water-soluble or water-swellable copolymers as claimed in

claim 1

, which comprises dissolving or dispersing the monomers corresponding to the repeating structural units of the formulae 1, 2 and 3 in a protic solvent, adding one or more crosslinkers having at least two olefinic double bonds to this solution or dispersion, and starting the polymerization by adding a free-radical-forming compound.

6. The use of the water-soluble or water-swellable copolymers as claimed in

claim 1

as thickeners.

7. A cosmetic or pharmaceutical preparation comprising a water-soluble or water-swellable copolymer as claimed in

claim 1

.