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Mixed buffer system for stabilizing polypeptide formulations

  • US 20010031726A1
  • Filed: 12/08/2000
  • Published: 10/18/2001
  • Est. Priority Date: 01/24/2000
  • Status: Active Grant
First Claim
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1. A solution formulation comprising:

  • (a) a physiologically tolerated mixed buffer system comprising TRIS combined with a buffering molecule which;

    (i) absorbs carbon dioxide; and

    (ii) does not contain a free amine group; and

    (b) a polypeptide.

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