System for determining analyte concentrations in body fluids
First Claim
1. A system for determining the concentration of at least one analyte in a liquid, the system comprising a first member and at least one second member each having a respective surface of which at least one has a recess and the first and second member are joined together so that the at least one recess is at least partially closed by the surface of the other member to form a channel, and at least one of the first and second members contain an exchange region that is formed to take up substances from the liquid, a sensor located downstream of the exchange region and formed to determine the concentration of an analyte, and wherein the system has at least one integrated reservoir which is connected to the channel.
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Accused Products
Abstract
The present invention concerns a system for determining the concentration of at least one analyte in a body fluid. The system has a first member and at least a second member of which at least one has a recess on its surface and the members are joined together in such a manner that the recess is closed by a surface of the other member to form a channel. The first and/or second member is composed at least partially of a membrane which is located either in the region of the recess or on the part of the other member that is opposite to the recess such that substances can be taken up from the surrounding fluid by means of the membrane. The system additionally has a sensor which can be used to determine the concentration of an analyte in the channel. Furthermore the system has at least one integrated reservoir which is connected to the channel.
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Citations
25 Claims
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1. A system for determining the concentration of at least one analyte in a liquid, the system comprising
a first member and at least one second member each having a respective surface of which at least one has a recess and the first and second member are joined together so that the at least one recess is at least partially closed by the surface of the other member to form a channel, and at least one of the first and second members contain an exchange region that is formed to take up substances from the liquid, a sensor located downstream of the exchange region and formed to determine the concentration of an analyte, and wherein the system has at least one integrated reservoir which is connected to the channel.
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12. A system for determining the presence of an analyte in a body fluid, the system comprising:
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a first member having a first surface, a second member having a second surface, at least one of the first and second surfaces including a recess, the second member being joined to the first member so that the recess is at least partially closed by the opposing surface to form a channel, an exchange region formed in at least one of the first and second members, the exchange region being in fluid communication with the channel and formed to receive substances from the body fluid therein, a reservoir in fluid communication with the channel, and an analyte sensor located downstream of the exchange region. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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21. A system for determining the presence of an analyte in a body fluid, the system comprising:
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a first member having a first surface and a reservoir having an opening extending through the first surface, a second member joined to the first member, the second member having a second surface facing the first surface and extending across the opening, the second surface including a dialysis channel having an inlet and an outlet, a perfusate channel extending from the reservoir to the dialysis channel and being at least partially covered by the first surface, and a dialysate channel extending from the outlet of the dialysis channel, and an analyte sensor in communication with the dialysate channel. - View Dependent Claims (22, 23, 24, 25)
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Specification