Endovascular stent graft

• US 20010041928A1
• Filed: 05/04/2001
• Published: 11/15/2001
• Est. Priority Date: 05/04/2000
• Status: Active Grant

• Current Assignee: Oregon Health & Science University
• Original Assignee: Oregon Health & Science University
• Inventors: Pavcnik, Dusan, Keller, Frederick S., Rosch, Josef
• Granted Patent: US 7,686,842 B2
• Time in Patent Office: Days
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching

Abstract

A stent graft (10) with a stent frame (12) having a plurality of stents (16) connected together with monofilament line (22). A covering (14) of collagen having an extracellular matrix (ECM), such as small intestine submucosa (SIS), is disposed through the inside and over the outside of the stent frame. The covering (14) is affixed to the stent frame (12) such as by being sutured onto the stent frame at the ends of the stent frame and also at the connections of the stent bodies, such as at eyelets (24).

Claims

1. A stent graft comprising:

at least one stent having a proximal end and a distal end and having a lumen extending therethrough between the proximal and distal ends, and

a covering of collagen having an extracellular matrix, secured to the at least one stent and extending therealong between the proximal and distal ends.

2. The stent graft of

claim 1

, wherein the covering extends along inside and outside surfaces of the at least one stent.

3. The stent graft of

claim 1

, comprising a plurality of stents connected together to form a stent frame with lumens of the respective stents coaligned to form a common continuous lumen extending from a distal stent frame end to a proximal stent frame end, and the covering extending therealong between the proximal and distal stent frame ends.

4. The stent graft of

claim 3

, wherein the stent frame has eyelets at the proximal and distal ends.

5. The stent graft of

claim 4

, wherein the covering is sutured to the stent frame using a filament of biocompatible material that extends through the eyelets.

6. The stent graft of

claim 3

, wherein each of said plurality of stents has eyelets at proximal and distal ends thereof, and the covering is sutured to the stent frame using a filament of biocompatible material that extends through the eyelets.

7. The stent graft of

claim 1

, wherein the covering is secured to the at least one stent at locations along the stent using a filament of biocompatible material, the locations being adapted to secure the filament in position against movement axially with respect to the stent during deployment at a treatment site of a patient.

8. The stent graft of

claim 1

, wherein the covering is a sleeve of small intestine submucosa material.

9. The stent graft of

claim 8

, wherein the sleeve is defined by connecting together along a seam, opposite edges of at least one flat tissue of the small intestine submucosa material.

10. The stent graft of

claim 1

, wherein the covering is a sleeve that initially has a length about equal to twice the length of the at least one stent, a first portion of the sleeve extends along an inside surface of the at least one stent, and a second portion of the sleeve is folded back over a proximal end of the at least one stent and then along an outside surface of the at least one stent to the distal end thereof.

11. The stent graft of

claim 1

, wherein the covering is disposed along the stent frame and therewithin.