Methods of applying antibiotic compounds to polyurethane biomaterials using textile dyeing technology
First Claim
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1. A composition comprising a urethane polymer reversibly bonded to a therapeutically active compound via one or more reactive groups of said polymer.
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Abstract
The invention provides urethane polymers bonded to therapeutically active compounds, such as antibiotics. The invention also features methods of applying therapeutically active compounds to polyurethane polymers using textile dyeing. These polymers may be used in a variety of clinical applications.
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42 Claims
- 1. A composition comprising a urethane polymer reversibly bonded to a therapeutically active compound via one or more reactive groups of said polymer.
- 13. A biocompatible device comprising a urethane polymer reversibly bonded to a therapeutically active compound via one or more reactive groups of said polymer.
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15. A wound dressing comprising a urethane polymer reversibly bonded to a therapeutically active compound via one or more reactive groups of said polymer.
- 16. A method of applying a therapeutically active organic compound to a urethane polymer, said method comprising incubating said polymer with said compound in a solution under conditions that result in reversible bonding of said compound to said polymer via one or more reactive groups of said polymer.
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