MEDICAMENT ADMINISTRATION SYSTEM
First Claim
1. A kit for preparing a pharmaceutical formulation for a man or an animal, which comprises a preparation of a biological active substance and a preparation containing liposomes or microspheres, which preparations are used for production of the pharmaceutical formulation to be administered by a medicament administration device that disperses the biological active substance in the air, said production being conducted by contacting the biological active substance with the liposomes or microspheres in an aqueous medium.
1 Assignment
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Accused Products
Abstract
A pharmaceutical formulation to be administered by a medicament administration device, which can maintain high stability of a biological active substance, is provided. In preparing the pharmaceutical formulation to be administered via mucous membrane, particularly a pharmaceutical formulation to be inhaled by utilizing a jet nebulizer, an ultrasonic nebulizer, a metered dose inhaler, or a dry powder inhaler, the adoption of the step of contacting the biological active substance with liposomes or microspheres in an aqueous medium enables the substance to be highly stabilized.
19 Citations
22 Claims
- 1. A kit for preparing a pharmaceutical formulation for a man or an animal, which comprises a preparation of a biological active substance and a preparation containing liposomes or microspheres, which preparations are used for production of the pharmaceutical formulation to be administered by a medicament administration device that disperses the biological active substance in the air, said production being conducted by contacting the biological active substance with the liposomes or microspheres in an aqueous medium.
- 15. A method for production of a pharmaceutical formulation for a man or an animal to be administered by a medicament administration device that disperses a biological active substance in the air, which comprises a step of contacting the biological active substance with liposomes or microspheres in an aqueous medium.
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16. A method for stabilizing a biological active substance by contacting the biological active substance with liposomes or microspheres, in the process for the production of a pharmaceutical formulation for a man or an animal to be administered by a medicament administration device that disperses the biological active substance in the air.
- 18. A pharmaceutical formulation for a man or an animal to be administered by a medicament administration device that disperses a biological active substance in the air, which was produced by contacting the biological active substance with liposomes or microspheres in an aqueous medium.
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20. A method for curative or prophylactic treatment of diseases of a man or an animal, which comprises administering to the man or the animal a pharmaceutical formulation for a man or an animal to be administered by a medicament administration device that disperses a biological active substance in the air, which was produced via a step of contacting the biological active substance with liposomes or microspheres in an aqueous medium.
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21. Use of liposomes or microspheres for the production of a pharmaceutical formulation for a man or an animal to be administered by a medicament administration device that disperses a biological active substance in the air, which was produced via a step of contacting the biological active substance with liposomes or microspheres in an aqueous medium.
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22. A metered dose inhaler or a dry powder inhaler, characterized in that it contains a pharmaceutical formulation for a man or an animal which was produced via a step of contacting the biological active substance with liposomes or microspheres in an aqueous medium.
Specification