Subcutaneous glucose measurement device

• US 20020016535A1
• Filed: 01/26/2001
• Published: 02/07/2002
• Est. Priority Date: 01/28/2000
• Status: Abandoned Application

• Current Assignee: Martin W. Blake, Micah D. Schmidt
• Original Assignee: Martin W. Blake, Micah D. Schmidt
• Inventors: Schmidt, Micah D., Martin, W. Blake
• Application Number:
  US09/770,131
• Publication Number:
  US 20020016535A1
• Time in Patent Office: Days
• US Class Current: 600/319
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

A subcutaneous glucose sensor comprising an infrared emitter which transmits light through a narrow sample of interstitial fluid held in a light transparent sample trough. The sensor can be incorporated with an insulin pump in order to create an insulin delivery and feedback measurement loop system.

Claims

1. A device for sensing the presence or concentration of a component in a fluid, comprising:

a. a power supply;

b. a processor;

c. at least one energy source;

d. at least one detector capable of detecting energy emitted by said energy source;

e. at least one sample trough capable of retaining an aliquot of fluid; and

,

f. a housing.

2. The device of claim 1, further comprising a telemetry device associated with said processor and capable of transmitting a signal from said processor to a remote receiving means.

3. The device of claim 2, wherein said remote receiving means is a pager capable of detecting a signal from said telemetry device.

4. The device of claim 3, wherein said signal transmitted from said telemetry device is an alarm signal transmitted in response to failure of said device to obtain measurements.

5. The device of claim 1, wherein said signal contains measurement data from said detector.

6. The device of claim 1, wherein said energy is light.

7. The device of claim 1, wherein said energy source is a light emitting diode.

8. The device of claim 1, wherein said energy source is a laser diode.

9. The device of claim 1, wherein said energy source generates energy in the near infrared range.

10. The device of claim 1, wherein said energy source further comprises a filter.

11. The device of claim 10, wherein said filter comprises a narrow bandwidth pass filter.

12. The device of claim 1, wherein said energy source provides energy at least two detectably distinct wavelengths.

13. The device of claim 1, wherein said detector is capable of detecting transmitted energy in the near infrared range.

14. The device of claim 1, wherein said detector is a pyroelectric detector.

15. The device of claim 1, further comprising a second detector capable of detecting a distinct wavelength of energy.

16. The device of claim 1, wherein said power supply is a battery.

17. The device of claim 1, wherein said battery is rechargeable.

18. The device of claim 1, wherein said trough is generally U-shaped and is defined in said housing.

19. The device of claim 1, wherein said trough is coated with a surfactant.

20. The device of claim 4, wherein said light has a wavelength of the mid-infrared.

21. The device of claim 4, wherein said light has a wavelength of from about 9 μ

m to about 10 μ

m.

22. The device of claim 1, wherein said component is glucose.

23. The device of claim 1, wherein said fluid is hemoglobin, plasma, tears, semen, or urine.

26. The method of claim 25, further comprising a step h. transmitting data containing the calculated concentration to a remote device.

24. An apparatus for delivering insulin and sensing the presence or concentration of glucose or other component in a fluid, comprising:

a. a power supply;

b. a processor;

c. at least one energy source;

d. at least one detector capable of detecting energy emitted by said energy source;

e. at least one sample trough capable of retaining an aliquot of fluid;

f. a housing; and

,

g. an insulin delivery apparatus comprising

i) a reservoir capable of holding an amount of insulin,

ii) means for delivering said insulin from said reservoir to a patient, said means comprising a pump, and

iii) an insulin delivery processor for determining when to actuate said pump to deliver an amount of insulin,

such that said insulin delivery processor is in communication with said device processor to provide a feedback loop between said sensing device and said delivery apparatus to maintain proper insulin level.

25. A method of detecting and measuring a component of a fluid, comprising the steps of:

a. providing a device comprising

iv) a housing,

v) a power supply,

vi) a processor,

vii) at least one energy source,

viii) at least one detector capable of detecting the energy emitted by the energy source, and

ix) at least one sample trough associated with the housing capable of retaining an effective amount of the fluid;

b. causing an aliquot of fluid to be retained within the trough;

c. emitting energy from the energy source so as to impinge on the fluid in the trough;

d. detecting the energy passing through the fluid in the trough;

e. transmitting an output signal from the detector to the processor;

f. interpreting the output signal;

g. determining the presence or concentration of the component in the fluid aliquot.