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Process for identification of genes encoding proteins having cell proliferation-promoting activity

  • US 20020019005A1
  • Filed: 08/02/2001
  • Published: 02/14/2002
  • Est. Priority Date: 02/18/1999
  • Status: Abandoned Application
First Claim
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1. A process for identifying a cell proliferation gene comprising the steps of:

  • (a) selecting a growth proficient revertant cell from a plurality of cultured cells arrested for growth, said growth arrested cells transformed with a library comprising a plurality of nucleic acid sequence inserts, wherein at least one insert from the library encodes a perturbagen within said revertant cell that results in said reversion to growth proficiency; and

    (b) identifying one or more genes or gene products in said revertant cell that cause said reversion to growth proficiency.

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