Expandable implant devices for filtering blood flow from atrial appendages
First Claim
1. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
- a membrane tube having at least a first closed end wherein said first closed end comprises a blood-permeable filter; and
an expandable structure disposed in said tube, said structure having a collapsed configuration and an expanded configuration, wherein said device is insertable in said appendage while said expandable structure is in said collapsed configuration, and wherein when said expandable structure is in said expanded configuration said closed end covers the ostium of said atrial appendage and portions of said membrane tube are pressed outwards against the interior walls of said atrial appendage anchoring said device therein.
1 Assignment
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Accused Products
Abstract
Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region. An expandable component structure in the device may include a blood-permeable filter element. The device may be deployed so that this component structure covers the ostium so as to direct the blood flow to pass through the filter element. The filter elements used in the devices may have hole size distributions selected to filter out harmful-size emboli. The filter elements may be embedded in elastic material so that hole-size distributions remain substantially unaffected by expansion of the device structures. Anchors attached to a component structure engage tissue surrounding the device and maintain the devices in position. The anchors may include inflatable anchors which engage interior walls of the atrial appendage.
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Citations
49 Claims
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1. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
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a membrane tube having at least a first closed end wherein said first closed end comprises a blood-permeable filter; and
an expandable structure disposed in said tube, said structure having a collapsed configuration and an expanded configuration, wherein said device is insertable in said appendage while said expandable structure is in said collapsed configuration, and wherein when said expandable structure is in said expanded configuration said closed end covers the ostium of said atrial appendage and portions of said membrane tube are pressed outwards against the interior walls of said atrial appendage anchoring said device therein. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 19, 20)
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13. A method for filtering blood flowing through the ostium of an atrial appendage, comprising:
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providing a device comprising a membrane tube having at least a first closed end wherein said first closed end comprises a blood-permeable filter;
inserting said device in said appendage;
positioning said closed end to cover said ostium; and
anchoring said device in said atrial appendage.
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18. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
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a cover comprising;
a filter element having a predetermined size; and
an expandable membrane attached to said filter element; and
an expandable structure for deploying said cover, wherein said expandable membrane stretches as said cover is deployed and allows said predetermined size to remain substantially unchanged.
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21. A method for filtering blood flowing through the ostium of an atrial appendage, comprising:
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providing a cover comprising an expandable membrane attached to a filter element having a predetermined size;
providing an expandable structure to deploy said cover across said ostium; and
positioning said cover across said ostium using said expandable structure, wherein said positioning comprises stretching said expandable membrane such that said predetermined size is substantially unchanged.
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22. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
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an expandable structure for covering said ostium; and
anchors disposed on the outer periphery of said expandable, wherein expandable structure has an axial length less than about the combined lengths of said ostium and a neck region of said atrial appendage leading to said ostium, wherein said expandable structure comprises a blood-permeable filter, and wherein said anchors engage surrounding ostium wall tissue. - View Dependent Claims (23, 24, 25, 26, 28, 29, 30, 31, 32)
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27. A method for filtering blood flowing through the ostium of an atrial appendage, comprising:
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providing an expandable structure comprising a blood-permeable filter, said expandable structure having an axial length less than about the length of an ostium;
providing anchors attached to said expandable structure;
disposing said expandable structure within said ostium;
positioning said expandable structure to cover said ostium; and
expanding said expandable structure so that said anchors engage surrounding ostium wall tissue.
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33. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
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a first structure comprising a blood-permeable filter element; and
a second structure attached to said first structure, said rear structure comprising at least one inflatable anchor set, wherein said first structure is deployed across said ostium, and wherein said inflatable anchor set when inflated engages interior wall tissue of said atrial appendage to secure said device in its deployed position. - View Dependent Claims (34, 35, 36, 37, 39)
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38. A method for filtering blood flowing through the ostium of an atrial appendage, comprising:
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providing a device comprising;
a first structure comprising a blood-permeable filter element; and
a second structure attached to said first structure, said second structure comprising at least one inflatable anchor set;
positioning said first structure to cover said ostium;
disposing said second structure interior to said atrial appendage; and
inflating said anchor set expanding so that said anchors engage surrounding atrial appendage wall tissue.
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40. A device for filtering blood flowing through the ostium of an atrial appendage, comprising:
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an expandable structure comprising;
a first portion having a blood-permeable filter element; and
a second portion having a cylindrical shape; and
anchors disposed on at least part of the exterior surface of said second portion, wherein when said device is deployed in about the vicinity of said ostium by expanding said expandable structure said first portion covers said ostium to direct said blood flow through said filter element and said anchors engage surrounding wall tissue. - View Dependent Claims (41, 42, 43, 44, 45, 46, 47, 49)
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48. A method for filtering blood flow through the ostium of an atrial appendage, comprising:
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providing a device comprising;
an expandable structure, said expandable structure comprising;
a first portion having a blood-permeable filter element; and
a second portion having a cylindrical shape; and
anchors disposed on at least part of the exterior surface of said second portion; and
deploying said device in about the vicinity of said ostium wherein said deploying comprises;
positioning said first portion to cover said ostium; and
expanding said expandable structure so that said anchors engage surrounding wall tissue.
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Specification