Combined micro-macro brain stimulation lead and method of using same
First Claim
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1. A brain stimulation lead, comprising:
- a macro segment having an opening disposed therein; and
a micro segment movably positioned within the macro segment, the micro segment being movable between a retracted position when the micro segment is housed within the macro segment and an extended position when the micro segment extends through the opening of the macro segment.
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Abstract
A lead for brain stimulation comprising a macro segment having a macro electrode for test stimulation and subsequent chronic stimulation, and a micro segment having a micro electrode for single cell recording is described. Methods for using the lead to stimulate brain tissue and to identify functional boundaries within brain tissue are also provided.
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Citations
24 Claims
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1. A brain stimulation lead, comprising:
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a macro segment having an opening disposed therein; and
a micro segment movably positioned within the macro segment, the micro segment being movable between a retracted position when the micro segment is housed within the macro segment and an extended position when the micro segment extends through the opening of the macro segment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 17, 18)
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13. A method of stimulating brain tissue, comprising:
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providing a lead comprising a macro segment including an opening disposed therein and a macro electrode adjacent the opening, a micro being segment movably positioned within the macro segment;
retracting the micro segment into the opening in the macro segment;
establishing a trajectory path within brain tissue;
inserting the lead along the trajectory path while the micro segment is in a retracted position; and
stimulating the brain tissue with the macro electrode.
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15. A method of identifying functional boundaries between brain structures, comprising:
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providing a lead comprising a macro segment including an opening disposed therein and a macro electrode adjacent the opening, a micro segment being movably positioned within the macro segment, the micro segment comprising a micro-electrode disposed at a distal end thereof;
retracting the micro segment into the opening;
establishing a trajectory path within brain tissue;
inserting the lead along the trajectory path while the micro segment is retracted;
extending the micro segment through the opening;
recording cell discharge patterns with the micro-electrode; and
identifying functional boundaries based on the cell patterns.
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16. A brain stimulation system, comprising:
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a lead comprising a macro segment having an opening disposed therein;
a micro segment movably positioned within the macro segment, the micro segment being movable between a retracted position when the micro segment is housed within the macro segment and an extended position when the micro segment extends through the opening of the macro segment;
at least one electrode adjacent the opening of the macro segment configured to permit test stimulation of brain tissue; and
at least one electrode disposed near a distal end of the micro segment configured to permit single cell recording.
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19. A method of stimulating brain tissue, comprising:
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retracting a micro segment into a macro segment;
creating a trajectory path within brain tissue;
inserting a macro segment along the trajectory path while the micro segment is in a retracted position;
extending the micro segment;
recording cell discharge patterns with the micro-electrode;
identifying functional boundaries based on the cell discharge patterns; and
stimulating the brain tissue with the macro electrode within the functional boundaries.
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20. A brain stimulation lead, comprising:
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identifying means for determining functional boundaries of brain tissue;
means for performing test stimulation of brain tissue; and
means for removing the identifying means from a brain tissue site during test stimulation. - View Dependent Claims (21, 22)
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23. A brain stimulation lead comprising:
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identifying means for determining functional boundaries of brain tissue;
means for performing test stimulation of brain tissue; and
means for housing the identifying means.
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24. A system for brain stimulation comprising:
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identifying means for determining functional boundaries of brain tissue;
means for performing test stimulation of brain tissue;
means for housing the identifying means; and
means for removing the identifying means from a brain tissue site during test stimulation.
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Specification