Absorbable adhesive compositions
First Claim
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1. A biocompatible adhesive composition, comprising:
- a first monomer species; and
a second monomer species different from said first monomer species, wherein at least said first monomer species is absorbable, and an absorption rate of said first monomer species is different from an absorption rate of said second monomer species.
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Abstract
A method of treating living tissue includes applying to living tissue a biocompatible adhesive composition, where the adhesive composition contains at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelerator, wherein the polymerization initiator or accelerator is a quaternary amine, or where the adhesive composition contains a mixture of two monomer species having different absorption rates.
76 Citations
68 Claims
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1. A biocompatible adhesive composition, comprising:
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a first monomer species; and
a second monomer species different from said first monomer species, wherein at least said first monomer species is absorbable, and an absorption rate of said first monomer species is different from an absorption rate of said second monomer species. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 19, 46)
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18. A method of treating living tissue, comprising:
applying to living tissue a biocompatible adhesive composition comprising at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelerator, wherein said polymerization initiator or accelerator is a purified benzalkonium chloride.
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20. A method of treating living tissue, comprising:
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applying to living tissue a biocompatible adhesive composition comprising;
at least one alkyl ester cyanoacrylate monomer;
a second monomer species having an absorption rate different from an absorption rate of said at least one alkyl ester cyanoacrylate monomer; and
a polymerization initiator or accelerator, wherein said polymerization initiator or accelerator is a quaternary amine. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 60, 61, 62, 63, 64, 65, 66, 67)
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28. A kit comprising a saleable package comprising:
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a first monomer species;
a second monomer species different from said first monomer species; and
a polymerization initiator or accelerator for at least one of said first and second monomer species, wherein at least said first monomer species is absorbable, and an absorption rate of said first monomer species is different from an absorption rate of said second monomer species.
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59. A biocompatible adhesive composition, comprising:
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at least one alkyl ester cyanoacrylate monomer;
a second monomer species having an absorption rate different from an absorption rate of said at least one alkyl ester cyanoacrylate monomer; and
a polymerization initiator or accelerator, wherein said polymerization initiator or accelerator is a quaternary amine.
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68. A polymerized film formed from the polymerization of a first monomer species and a second monomer species different from said first monomer species, wherein at least said first monomer species is absorbable and an absorption rate of said first monomer species is different from an absorption rate of said second monomer species.
Specification