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Methods and apparatus for characterization of single polymers

  • US 20020039737A1
  • Filed: 06/06/2001
  • Published: 04/04/2002
  • Est. Priority Date: 08/13/1999
  • Status: Active Grant
First Claim
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1. A method for determining velocity of an elongated polymer, the method comprising:

  • a) defining at least one detectable region on the polymer;

    b) causing relative movement of the elongated polymer through a plurality of linearly sequential detection zones, each separated a predetermined distance, to cause interactions between the detectable region and the detection zones, thereby producing a plurality of signal amplitude profiles, each signal amplitude profile being produced at a different detection zone and comprising data acquired before, during and after each interaction;

    c) measuring each of the signal amplitude profiles in a time-correlated manner; and

    d) analyzing the time-correlated measurements to determine the velocity of the polymer.

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