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Device and method for lysing cells, spores, or microorganisms

  • US 20020039783A1
  • Filed: 11/07/2001
  • Published: 04/04/2002
  • Est. Priority Date: 12/24/1998
  • Status: Active Grant
First Claim
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1. A device for lysing components of a fluid sample, the device comprising:

  • a) a cartridge having;

    i) an inlet port for introducing the sample into the cartridge;

    ii) a lysing chamber containing a membrane or filter for capturing the sample components as the sample flows through the lysing chamber;

    iii) an outlet port for exit of the sample from the lysing chamber; and

    iv) beads in the lysing chamber for rupturing the sample components; and

    b) an ultrasonic transducer for transferring ultrasonic energy to the lysing chamber to agitate the beads and thereby rupture the components, wherein the transducer is coupled to a wall of the lysing chamber.

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