Led light source-based instrument for non-invasive blood analyte determination

• US 20020041166A1
• Filed: 09/17/2001
• Published: 04/11/2002
• Est. Priority Date: 09/26/2000
• Status: Active Grant

• Current Assignee: GLT Acquisition Corporation
• Original Assignee: Sensys Medical, Inc. (Sensys Medical Limited)
• Inventors: Grubisic, Dragan
• Granted Patent: US 6,816,241 B2
• Time in Patent Office: Days
• US Class Current: 315/291
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 2562/046 in a matrix array
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters

Abstract

A compact, lightweight instrument for non-invasive blood analyte determination employs a light source incorporating an assembly of LED'"'"'s interconnected within a thermally stable substrate. A large diameter mixer couples the signal to a fiber optic probe for delivering the signal to a tissue measurement site. Back-diffused light is collected and dispersed across an array of photo detectors in a miniature spectrometer instrument. A high-speed DSP executes an algorithm for predicting concentration of a target analyte, which is output to a LCD display. Instrument control is by means of keypad or voice recognition.

High conversion efficiency of the light source results in extremely low power dissipation and virtually no heat generation, making incorporation of the light source and the spectrometer into a single unit practicable. High-speed pulsing of the signal allows application of high-sensitivity, synchronous detection techniques. Speed and flexibility in sequencing LED'"'"'s allows simultaneous measurement and skin temperature control.

Claims