Novel human secreted proteins and polynucleotides encoding the same

• US 20020042504A1
• Filed: 03/20/2001
• Published: 04/11/2002
• Est. Priority Date: 03/20/2000
• Status: Active Grant

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Wang, Xiaoming, Scoville, John, Wilganowski, Nathaniel L., Walke, D. Wade, Hilbun, Erin, Donoho, Gregory, Turner, C. Alexander Jr.
• Granted Patent: US 6,815,538 B2
• Time in Patent Office: Days
• US Class Current: 536/23.2
• CPC Class Codes: C07K 14/4702 Regulators; Modulating activity

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in thrapeutic, diagnostic, and pharmacogenomic applcations.

Claims

1. An isolated nucleic acid molecule comprising at least 24 contiguous bases of nucleotide sequence first disclosed in SEQ ID NO:

1.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

2; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

1 or the complement thereof.

3. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

2.

4. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

4.

5. An isolated nucleic acid molecule comprising at least 24 contiguous bases of nucleotide sequence first disclosed in SEQ ID NO:

6.

6. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence shown in SEQ ID NO;

7; and

(b) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

6 or the complement thereof.

7. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

7.

8. An isolated nucleic acid molecule comprising at least 24 contiguous bases of nucleotide sequence first disclosed in SEQ ID NO:

8.

9. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(c) encodes the amino acid sequence shown in SEQ ID NO;

9; and

(d) hybridizes under stringent conditions to the nucleotide sequence of SEQ ID NO;

8 or the complement thereof.

10. An isolated nucleic acid molecule comprising a nucleotide sequence that encodes the amino acid sequence shown in SEQ ID NO:

9.