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Controlled- release dosage forms of azithromycin

  • US 20020044965A1
  • Filed: 03/09/2001
  • Published: 04/18/2002
  • Est. Priority Date: 05/06/1994
  • Status: Active Grant
First Claim
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1. A controlled release dosage form comprising azithromycin and a pharmaceutically acceptable carrier which, following Ingestion by a mammal in need thereof, releases azithromycin to said mammal'"'"'s gastrointestinal tract at a rate such that the total amount of azithromycin released therein is:

  • not more than about 4 mg of azithromycin per kg of mammal weight in the first 15 minutes after ingestion, not more than about 10 mg of azithromycin per kg of mammal weight in the first hour after ingestion, not more than about 20 mg of azithromycin per kg of mammal weight in the first 2 hours after ingestion, not more than about 30 mg of azithromycin per kg of mammal weight in the first 4 hours after ingestion, and not more than about 40 mg of azithromycin per kg of mammal weight in the first 6 hours after ingestion

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