Surgical repair of tissue defects
First Claim
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1. A method for repairing a defect in living mammalian tissue comprising:
- covering a tissue defect and surrounding tissue with a prosthetic by placing said prosthetic over said defect and against said surrounding tissue; and
applying a surgical adhesive to said prosthetic on said surrounding tissue on at least one location on said prosthetic and said surrounding tissue to permit surrounding tissue and said prosthetic adhere to each other.
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Abstract
A method for repairing a defect in living mammalian tissue comprising: covering a tissue defect and surrounding tissue with a prosthetic by placing the prosthetic over the defect and against the surrounding tissue. The method includes applying a surgical adhesive to the prosthetic on the surrounding tissue on at least one location on the prosthetic and the surrounding tissue so that surrounding tissue and the prosthetic adhere to each other.
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Citations
27 Claims
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1. A method for repairing a defect in living mammalian tissue comprising:
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covering a tissue defect and surrounding tissue with a prosthetic by placing said prosthetic over said defect and against said surrounding tissue; and
applying a surgical adhesive to said prosthetic on said surrounding tissue on at least one location on said prosthetic and said surrounding tissue to permit surrounding tissue and said prosthetic adhere to each other. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 15, 16, 17, 19, 20, 21)
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14. A method for repairing a defect in living mammalian tissue comprising:
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attaching a syringe to a catheter;
delivering a surgical adhesive through said catheter from said syringe to said tissue defect in a mammal, and covering said tissue defect and surrounding tissue with said surgical adhesive, said surgical adhesive being mixed with a plurality of filaments of a second solid substance so that when said adhesive cures to said tissue said second solid provides a randomized matrix fully encapsulated by said adhesive.
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18. An implantable prosthesis for repairing a tissue or muscle wall defect in a comprising:
a flexible porous plug arranged to retain a surgical adhesive for creating a tissue bond, said plug arranged to fit within and occlude a tissue or muscle wall defect wherein at least a portion of said flexible plug includes a cavity which permits delivery of an additional adhesive into said plug so that said plug conforms to any irregularities in said tissue or muscle wall defining the defect to form a cured solid plug of adhesive and a flexible plug, said flexible plug being compressible radially upon insertion into the defect from a first configuration which is larger than the defect to a second configuration which closely approximates the shape of the defect.
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22. A tissue defect repair patch for implanting within a patient, comprising:
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at least one first layer of inert synthetic mesh material sized and shaped to extend across and beyond a tissue aperture in a patient;
a resilient support member adjacent a periphery of said first layer for creating tension in said first layer, said support member being carried by said first layer so as to remain implanted with said first layer in the patient;
said first layer of inert synthetic mesh material having a periphery extending beyond said support member to define a border which has a free outer edge to fill uneven voids in a patient'"'"'s tissue. said first layer of inert synthetic mesh material having a surgical adhesive impregnated between interstices of said first layer to effect a bond between mesh and tissue. - View Dependent Claims (24, 27)
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23. A tissue defect repair patch for implanting within a patient, comprising:
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at least one layer of flexible, inert synthetic non-porous sheet sized and shaped to extend across and beyond a tissue aperture in a patient;
a resilient support member adjacent a periphery of the layer for creating tension in the layer, the support member being carried by the layer so as to remain implanted with the layer in the patient; and
the layer of inert synthetic sheet having a periphery extending beyond the support member, defining a border which has a free outer edge to fill uneven voids in a patient'"'"'s tissue; and
the layer of inert synthetic sheet having a surgical adhesive coating the sheet to effect a bond between mesh and tissue.
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25. A plug formed from a non-porous inflatable structure of conical geometry, in which surgical adhesive is injected to form an inflatable structure to fill a tissue defect in mammalian tissue, the inflatable structure allowing for permeation of fluids into its interior, thus effecting a cure of the surgical adhesive.
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26. A plug formed from a porous inflatable structure of conical geometry, in which surgical adhesive is injected to form the inflatable structure to fill a defect, the porosity of the inflatable structure such that adhesive slowly flows from the surface, such porosity being between 25-50 microns for a surgical adhesive with a viscosity of 3000 cps, said adhesive effecting a bond between said plug and said tissue, said inflatable structure allowing for permeation of fluids into its interior, thus effecting a cure of said surgical adhesive.
Specification