FLUID-BASED AGENT DELIVERY DEVICE WITH SELF-EXPANDING DELIVERY ELEMENT
First Claim
1. A device for delivering a fluid-based agent in a lumen, in a mammalian body, the device comprising:
- a) a housing including an elongated bore having a diameter, the housing being sized to fit in a lumen in a mammalian body; and
b) a delivery element including a proximal portion, a distal portion, and a wall defining (i) a fluid passage extending between the proximal portion and the distal portion and (ii) a plurality of apertures in fluid communication with the fluid passage at the distal portion, the housing being selectively movable relative to the delivery element between a first position in which the distal portion is disposed in the bore and a second position in which the distal portion extends exteriorly of the bore;
wherein the distal portion is constrained in a first shape in the first position, and the distal portion self-expands to a second shape having a diameter greater than the diameter of the bore in response to the housing being moved to the second position.
1 Assignment
0 Petitions
Accused Products
Abstract
A device suitable for delivering a fluid-based agent in a body lumen in a mammalian body comprises a housing including an elongated bore, and a delivery element. The delivery element includes a proximal portion, a distal portion preferably comprised of a superelastic material, and a wall. The wall defines (i) a fluid passage extending between the proximal portion and the distal portion, and (ii) a plurality of apertures in fluid communication with the fluid passage at the distal portion. The housing is selectively movable relative to the delivery element between a first position in which the distal portion is disposed in the bore, and a second position in which the distal portion is disposed exteriorly of the bore. The distal portion is constrained inside the bore in the first position, and the distal portion self-expands in the second position. The apertures contact the vessel wall in the second position to enable the agent to be delivered directly to the wall of the lumen.
11 Citations
31 Claims
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1. A device for delivering a fluid-based agent in a lumen, in a mammalian body, the device comprising:
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a) a housing including an elongated bore having a diameter, the housing being sized to fit in a lumen in a mammalian body; and
b) a delivery element including a proximal portion, a distal portion, and a wall defining (i) a fluid passage extending between the proximal portion and the distal portion and (ii) a plurality of apertures in fluid communication with the fluid passage at the distal portion, the housing being selectively movable relative to the delivery element between a first position in which the distal portion is disposed in the bore and a second position in which the distal portion extends exteriorly of the bore;
wherein the distal portion is constrained in a first shape in the first position, and the distal portion self-expands to a second shape having a diameter greater than the diameter of the bore in response to the housing being moved to the second position. - View Dependent Claims (2, 3, 4, 5, 6, 7, 17)
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8. A device for delivering a fluid-based agent in a lumen in a mammalian body, the device comprising:
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a) a housing including an elongated bore having a diameter, the housing being sized to fit in a lumen in a mammalian body; and
b) a delivery element including a proximal portion, a distal portion and a wall defining (i) a fluid passage extending between the proximal portion and the distal portion and (ii) a plurality of apertures in fluid communication with the fluid passage at the distal portion, the housing being movable relative to the delivery element between a first position in which the distal portion is disposed in the bore and a second position in which the distal portion extends exteriorly of the bore;
wherein (i) the distal portion of the delivery element is comprised of a superelastic material which superelastically forms stress-induced martensite at about the mammalian body temperature, and (ii) the distal portion assumes a superelastically constrained first shape in the first position, and the distal portion superelastically transforms to a second shape having a diameter greater than the diameter of the bore in response to the housing being moved to the second position. - View Dependent Claims (9, 10, 11, 12, 13, 15, 16, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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14. A device for delivering a fluid-based agent to a wall of a lumen in a mammalian body, the device comprising:
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a) a housing defining an elongated bore having a diameter, the housing being sized to fit in a lumen in a mammalian body; and
b) a delivery element including a proximal portion, a distal portion comprised of a superelastic material that superelastically forms stress-induced martensite at about mammalian body temperature, and a wall defining (i) a fluid passage extending between the proximal portion and the distal portion and (ii) a plurality of apertures in fluid communication with the fluid passage at the distal portion, the housing being movable relative to the delivery element between a first position in which the distal portion is disposed in the bore and a second position in which the distal portion extends exteriorly of the bore;
wherein (i) the distal portion assumes a superelastically constrained shape having a diameter approximately equal to the diameter of the bore in the first position, and (ii) the distal portion superelastically transforms to a second shape in response to the housing being moved to the second position, the second shape having a diameter greater than the diameter of bore such that at least some of the apertures contact the wall of the lumen, thereby enabling the fluid-based agent to be delivered directly to the wall of the lumen via the apertures.
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Specification