Polysaccharide coating of contact lenses
First Claim
1. A contact lens having a surface coating comprising a compatible sulfated polysaccharide.
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Abstract
The present invention provides a method of modifying surfaces of contact lenses to reduce bacterial, fungal or viral concentration and adherence. The method of the invention comprises the coating of a contact lens surface with a sulfated polysaccharide such as heparin to reduce the concentration of microorganisms, as well as bacterial, fungal or viral adherence. The invention further relates to compositions comprising contact lenses for correcting vision deficiencies of the eye coated with a sulfated polysaccharide such as heparin. Contact lens surfaces as provided in accordance with this invention have a coating of sulfated polysaccharide which reduces the concentration of microorganisms of all types and prevents the adherence of bacteria, fungi or viruses to the lens surface thereby reducing the potential for infection.
16 Citations
14 Claims
- 1. A contact lens having a surface coating comprising a compatible sulfated polysaccharide.
- 9. A method of preparing a contact lens having a surface coating comprising a compatible sulfated polysaccharide, the method comprising the steps of first exposing an uncoated lens to a plasma to generate a plasma-treated lens having a surface with constituents selected from the group consisting essentially of amines, carboxylic acids, active free radicals, and passive free radicals, and thereafter bonding the sulfated polysaccharide to the plasma-treated lens surface.
Specification