Method of administering a therapeutically active substance
First Claim
1. A method for administering a therapeutically active component to a target tissue in a subject, the method comprising the steps of:
- providing a brachytherapy seed comprising a non-metal biocompatible component, a therapeutically active component comprising a non-radioactive drug, and a radiopaque marker, said biocompatible component being (a) physically associated with a therapeutically active component and (b) in contact with said radiopaque marker, wherein said brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge);
providing a brachytherapy implantation instrument comprising at least one brachytherapy implantation needle having a bore having an interior diameter of less than about 2.7 millimeters (10 gauge), and being adapted to accept the brachytherapy seed into the bore of the at least one brachytherapy implantation needle and deliver the accepted implantation device into a target tissue;
introducing the brachytherapy seed into the bore of the at least one implantation needle of the brachytherapy implantation instrument;
introducing at least a portion of the at least one brachytherapy implantation needle into a target tissue in the subject; and
actuating the brachytherapy implantation instrument such that the brachytherapy seed is delivered through the bore of the brachytherapy implantation needle into the target tissue.
1 Assignment
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Accused Products
Abstract
A method for administering a therapeutically active component including a non-adioactive drug to a target tissue in a subject includes the steps of: (a) providing a brachytherapy seed having a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge); (b) providing a brachytherapy implantation instrument comprising at least one brachytherapy implantation needle having a bore having an interior diameter of less than about 2.7 millimeters (10 gauge), and being adapted to accept the brachytherapy seed into the bore of the at least one brachytherapy implantation needle and deliver the accepted implantation device into a target tissue; (c) introducing the brachytherapy seed into the bore of the at least one implantation needle of the brachytherapy implantation instrument; (d) introducing at least a portion of the at least one brachytherapy implantation needle into a target tissue in the subject; and (e) actuating the brachytherapy implantation instrument such that the brachytherapy seed is delivered through the bore of the brachytherapy implantation needle into the target tissue.
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Citations
8 Claims
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1. A method for administering a therapeutically active component to a target tissue in a subject, the method comprising the steps of:
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providing a brachytherapy seed comprising a non-metal biocompatible component, a therapeutically active component comprising a non-radioactive drug, and a radiopaque marker, said biocompatible component being (a) physically associated with a therapeutically active component and (b) in contact with said radiopaque marker, wherein said brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge);
providing a brachytherapy implantation instrument comprising at least one brachytherapy implantation needle having a bore having an interior diameter of less than about 2.7 millimeters (10 gauge), and being adapted to accept the brachytherapy seed into the bore of the at least one brachytherapy implantation needle and deliver the accepted implantation device into a target tissue;
introducing the brachytherapy seed into the bore of the at least one implantation needle of the brachytherapy implantation instrument;
introducing at least a portion of the at least one brachytherapy implantation needle into a target tissue in the subject; and
actuating the brachytherapy implantation instrument such that the brachytherapy seed is delivered through the bore of the brachytherapy implantation needle into the target tissue. - View Dependent Claims (2, 3, 4)
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5. A method administering a therapeutically active component to a target tissue in a subject, the method comprising the steps of:
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providing a brachytherapy seed comprising a sealed container, and a non-metal biocompatible component, and a therapeutically active component comprising a non-radioactive drug, said biocompatible component being physically associated with the therapeutically active component to form a combination product; and
said sealed container being made of a nonbiodegradable substance, housing a radioisotope, and being at least partially coated with the combination product, wherein said brachytherapy seed having a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge);
providing a brachytherapy implantation instrument comprising at least one brachytherapy implantation needle having a bore having an interior diameter of less than about 2.7 millimeters (10 gauge), and being adapted to accept the brachytherapy seed into the bore of the at least one brachytherapy implantation needle and deliver the accepted implantation device into a target tissue;
introducing the brachytherapy seed into the bore of the at least one implantation needle of the brachytherapy implantation instrument;
introducing at least a portion of the at least one brachytherapy implantation needle into a target tissue in the subject; and
actuating the brachytherapy implantation instrument such that the brachtherapy seed is delivered through the bore of the brachytherapy implantation needle into the target tissue. - View Dependent Claims (6, 7, 8)
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Specification