Techniques for selective activation of neurons in the brain, spinal cord parenchyma or peripheral nerve
First Claim
1. A cannula for use with a therapy delivery device for providing treatment therapy to a volume of neural tissue, the cannula comprising in combination:
- (a) a proximal end capable of receiving at least two leads;
(b) a body; and
(c) a distal end having at least two apertures, each aperture capable of directing at least one of the leads outwardly along a distinct predetermined trajectory.
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Abstract
The present invention discloses techniques capable of selectively affecting and adjusting a volume of neural tissue in the brain, parenchyma of the spinal cord, or a peripheral nerve. The invention preferably utilizes a lumen having at least one opening at its distal end that is capable of directing a lead outwardly along a predetermined trajectory. The lumen is capable of accepting a plurality of leads that can project outward in different directions from the distal end of the lumen. The leads have one or more electrodes at its ends and are thereby configured by the lumen in accordance with a predetermined two- or three-dimensional geometry. Anode/cathode relationships may be then established between the electrodes as desired by the operator to stimulate the neural tissue surrounding these electrodes. The operator may also adjust the stimulation to selectively stimulate the desired portion of the brain, spinal cord, peripheral nerve. In other embodiments, the present invention may be implemented to provide drug infusion. Sensor feedback may be implemented to adjust the treatment therapy.
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Citations
45 Claims
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1. A cannula for use with a therapy delivery device for providing treatment therapy to a volume of neural tissue, the cannula comprising in combination:
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(a) a proximal end capable of receiving at least two leads;
(b) a body; and
(c) a distal end having at least two apertures, each aperture capable of directing at least one of the leads outwardly along a distinct predetermined trajectory.
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2. A lead system for providing treatment therapy to a volume of neural tissue comprising in combination:
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(a) cannula having a lumen distal end, the lumen distal end having at least two openings, each opening capable of directing a lead outwardly along a distinct predetermined trajectory;
(b) at least two leads insertable within the cannula; and
(c) at least one therapy delivery element at a distal end of each lead. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11, 13, 14, 15, 17, 18, 19)
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12. A method for implanting leads to provide treatment therapy to a volume of neural tissue comprising the steps of:
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(a) positioning a cannula within a body of a patient, the cannula having at least two openings near a distal end, each opening capable of directing a lead outwardly along a distinct predetermined trajectory;
(b) inserting at least two leads into the cannula; and
(c) directing a distal end of each lead outwardly through one of the openings and along the distinct predetermined trajectory determined by the opening.
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16. A method for implanting leads to provide treatment therapy to a volume of neural tissue comprising the steps of:
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(a) implanting a cannula within a body of a patient;
(b) inserting first and second leads into the cannula;
(c) directing a first distal end of the first lead outwardly through the cannula and along a first distinct predetermined trajectory; and
(d) directing a second distal end of the second lead outwardly through the cannula and along a second distinct predetermined trajectory.
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20. A method of providing treatment therapy to a volume of neural tissue of a patient comprising the steps of:
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(a) implanting a cannula within a predetermined site of the patient;
(b) inserting at least two leads into the cannula and directing each lead outwardly through an opening along a distal end of the cannula, each lead extending from the cannula along a distinct predetermined trajectory; and
(c) positioning a therapy delivery element on the distal end of each lead to provide treatment therapy to the volume of neural tissue. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 29, 30, 31, 32, 33, 34, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45)
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28. A system for providing treatment therapy to a volume of neural tissue comprising in combination:
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(a) cannula having a lumen distal end, the lumen distal end having at least two openings, each opening capable of directing an object outwardly along a distinct predetermined trajectory;
(b) at least one lead insertable within the cannula and capable of being directed outwardly through one of the openings of the cannula and having at least one electrode at a distal end of the lead;
(c) at least one catheter insertable within the cannula and capable of being directed outwardly through another one of the openings of the cannula;
(d) a signal generator coupled to the lead for providing electrical stimulation to the neural tissue; and
(e) a drug delivery device coupled to the catheter for delivering at least one drug to the neural tissue.
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35. A method for providing treatment therapy to a volume of neural tissue comprising the steps of:
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(a) implanting a cannula within a body of a patient;
(b) inserting at least one lead into the cannula;
(c) directing a lead distal end of first lead outwardly through the cannula and along a first distinct predetermined trajectory;
(d) inserting at least one catheter into the cannula; and
(e) directing a catheter distal end of the catheter outwardly through the cannula and along a second distinct predetermined trajectory.
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Specification