Miniaturized integrated nucleic acid processing and analysis device and method
First Claim
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1. A miniature device comprising:
- a body having a reaction chamber disposed therein;
a resistive heater electrically connected to a power source for applying power to said heater;
a temperature sensor disposed on a surface of said body for determining a temperature within said reaction chamber; and
an appropriately programmed computer for monitoring said temperature and operating said power source to selectively apply said current across said heater.
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Abstract
A miniature device has a body including one, two or more reaction chambers. The reaction chambers are constructed for one or more of the following: sample acquisition, preparation or analysis. Preferably, a sample preparation reaction includes nucleic acid extraction, amplification, nucleic acid fragmentation, labeling, extension or a transcription.
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Citations
13 Claims
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1. A miniature device comprising:
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a body having a reaction chamber disposed therein;
a resistive heater electrically connected to a power source for applying power to said heater;
a temperature sensor disposed on a surface of said body for determining a temperature within said reaction chamber; and
an appropriately programmed computer for monitoring said temperature and operating said power source to selectively apply said current across said heater. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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Specification