Method and system for reducing arterial restenosis in the presence of an intravascular stent
First Claim
1. A method, comprising:
- sensing cardiac signals, where the cardiac signals include a cardiac cycle;
positioning a first electrode within an artery proximate an implanted intravascular stent;
positioning a second electrode at a remote position relative to the first electrode; and
delivering electrical energy between the first electrode and the second electrode during a predetermined portion of the cardiac cycle.
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Accused Products
Abstract
A first electrode is positioned within an artery proximate an implanted intravascular stent. A second electrode is positioned at a separate location relative the position of the first electrode. Electrical energy is then delivered between the first and the second electrodes to produce an electrical field adjacent the implanted intravascular stent. When a intravascular stent is implanted in a coronary artery, the delivery of the electrical energy is coordinated to cardiac cycles detected in sensed cardiac signals, where the delivery of the electrical energy between the first electrode and the second electrode occurs during a predetermined portion of the cardiac cycle.
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Citations
26 Claims
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1. A method, comprising:
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sensing cardiac signals, where the cardiac signals include a cardiac cycle;
positioning a first electrode within an artery proximate an implanted intravascular stent;
positioning a second electrode at a remote position relative to the first electrode; and
delivering electrical energy between the first electrode and the second electrode during a predetermined portion of the cardiac cycle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method, comprising:
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positioning at least a portion of a first electrode within a lumen of a stent;
positioning a second electrode at a remote position relative to the first electrode; and
delivering electrical energy between the first electrode and the second electrode. - View Dependent Claims (12, 14, 15, 16, 17, 18, 19)
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13. A system, comprising:
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an intravascular stent, wherein the intravascular stent is electrically conductive;
a first electrode coupled to a first lead connector;
a second electrode coupled to a second lead connector;
a pulse generator, wherein the pulse generator includes a programming circuit, a display screen, a data input device, a first and a second input/output socket, an electrogram analysis circuit, a microprocessor, and an energy source;
whereinthe programming circuit is coupled to the display screen, where the programming circuit controls the display screen to request parameter values for an electrical energy pulse;
the data input device is coupled to the programming circuit and the display screen, where the programming circuit receives the parameter values provided through the data input device;
the first lead connector is releasably coupled to the first input/output socket and the second lead connector is releasably coupled to the second input/output socket;
the electrogram analysis circuit is coupled to the first electrode and the second electrode coupled through the first and second lead connectors, where the electrogram analysis circuit receives a cardiac signal sensed between the first and second electrode, and where the electrogram analysis circuit detects cardiac complexes in the sensed cardiac signal;
the microprocessor is coupled to the programming circuit, the electrogram analysis circuit and the energy source, where the microprocessor receives the parameter values from the programming circuit and the cardiac complexes in the sensed cardiac signal from the electrogram analysis circuit, and controls the energy source to generate the electrical energy pulse having the parameter values for the intravascular stent when a predetermined portion of a cardiac complex occurs in the cardiac signal.
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20. A system, comprising:
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an intravascular stent, the intravascular stent being electrically conductive;
a first electrode coupled to a first lead connector;
a second electrode coupled to a second lead connector;
two or more surface electrocardiogram electrodes, wherein each of the two or more surface electrocardiogram electrodes is coupled to a lead connector of two or more lead connectors;
a pulse generator, wherein the pulse generator includes a programming circuit, a display screen, a data input device, a first and a second input/output socket, an electrogram analysis circuit, a microprocessor, and an energy source;
whereinthe programming circuit is coupled to the display screen, where the programming circuit controls the display screen to request parameter values for an electrical energy pulse;
the data input device is coupled to the programming circuit and the display screen, where the programming circuit receives the parameter values provided through the data input device;
the first lead connector is releasably coupled to the first input/output socket and the second lead connector is releasably coupled to the second input/output socket;
the electrogram analysis circuit is coupled to the two or more surface electrocardiogram electrodes through the two or more lead connectors, where the electrogram analysis circuit receives a cardiac signal sensed between the two or more surface electrocardiogram electrodes, and where the electrogram analysis circuit detects cardiac complexes in the sensed cardiac signal;
the microprocessor is coupled to the programming circuit, the electrogram analysis circuit and the energy source, where the microprocessor receives the parameter values from the programming circuit and the cardiac complexes in the sensed cardiac signal from the electrogram analysis circuit, and controls the energy source to generate the electrical energy pulse having the parameter values for the intravascular stent when a predetermined portion of a cardiac complex occurs in the cardiac signal. - View Dependent Claims (21, 22, 23, 24, 25, 26)
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Specification