Method for making contact to cells present in a liquid environment above a substrate
First Claim
Patent Images
1. A microelement device comprising a substrate;
- a plurality of electrical microelements arranged on said substrate adapted for electrically contacting biological cells present in a liquid environment;
means selected from the group consisting of means for guiding said cells toward said microelements, means for mechanically attracting said cells toward said microelements, and means for isolating the cells.
1 Assignment
0 Petitions
Accused Products
Abstract
A microelement device has a plurality of microelements, which may be configured as microelectrodes, arranged on a substrate and adapted for making contact to cells present in a liquid environment. The cells are guided onto the microelectrodes, are isolated or are mechanically attracted to the microelectrodes. A negative-pressure force or a hydrodynamic force may be applied on the cells. Also described are a method for making contact to the cells, and a method for manufacturing the microelement device is disclosed.
87 Citations
47 Claims
-
1. A microelement device comprising
a substrate; -
a plurality of electrical microelements arranged on said substrate adapted for electrically contacting biological cells present in a liquid environment;
means selected from the group consisting of means for guiding said cells toward said microelements, means for mechanically attracting said cells toward said microelements, and means for isolating the cells. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 24, 25, 27, 28)
-
- 22. The device as defined in 17, wherein the base plate comprises at least a lower signal processing plate and an element plate located thereabove.
-
30. A method for making contact to cells present in a liquid environment above a substrate, said method comprising the steps of:
-
creating electrical microelements;
creating a contact between said cells and said microelements; and
creating a force for guiding the cells. - View Dependent Claims (31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
-
-
42. A method for manufacturing a microelement device having a plurality of electrical microelements which are arranged on a substrate, said method comprising the steps of:
-
providing a base plate; and
providing a cover plate located thereabove. - View Dependent Claims (43, 44, 45, 46, 47)
-
Specification