Covered, coiled drug delivery stent and method
First Claim
1. A covered, coiled drug delivery stent comprising:
- a coiled, radially-expandable stent body comprising an outer surface;
a porous covering overlying the outer surface;
a drug associated with the porous covering; and
said stent, porous covering and drug constituting a stent subassembly.
5 Assignments
0 Petitions
Accused Products
Abstract
A covered, coiled drug delivery stent (145) includes a coiled, radially-expandable stent wall or body (139) with a porous covering overlying the outer surface (139A) of the stent body. A drug (147) may be associated with the porous covering by, for example, being in the form of a porous covering/drug matrix (141) or being a layer above or below the porous covering. Structure may be used to delay the migration of the drug to the patient by, for example, using a protective layer (143) to cover the stent body, porous covering, and drug. The protective layer may be removed by being biodegradable, or by being at least partially pulled off of the structure. The drug may be an integral part of a biodegradable material so that the drug is exposed only when the biodegradable material biodegrades. The drug may also be within biodegradable microencapsulation material.
393 Citations
27 Claims
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1. A covered, coiled drug delivery stent comprising:
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a coiled, radially-expandable stent body comprising an outer surface;
a porous covering overlying the outer surface;
a drug associated with the porous covering; and
said stent, porous covering and drug constituting a stent subassembly. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A covered, coiled drug delivery stent comprising:
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a coiled, radially-expandable stent body comprising spaced-apart parallel side elements joined by connector elements and an outer surface;
a porous covering, comprising ePTFE, overlying the outer surface;
a drug associated with the porous covering;
said stent body, porous covering, and drug constituting a stent subassembly; and
a biodegradable protective layer covering said stent subassembly so that when said protective layer biodegrades, said drug may migrate from said stent subassembly.
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21. A method for delivering a drug to a patient comprising:
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directing a covered, coiled stent subassembly, comprising a drug associated with a porous covering which overlies a coiled, radially-expandable prosthesis, to a target site within a patient;
waiting for a protective material, initially shielding the drug, to be effectively removed from said stent subassembly thereby exposing said drug; and
permitting said the drug to migrate from said stent subassembly for interaction with the patient. - View Dependent Claims (22, 23, 24, 25, 26, 27)
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Specification