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Co-administration of a thrombolytic and an anti-CD18 antibody in stroke

  • US 20020081294A1
  • Filed: 12/20/2000
  • Published: 06/27/2002
  • Est. Priority Date: 01/23/1996
  • Status: Abandoned Application
First Claim
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1. A method for increasing cebral blood flow and/or reducing interfact size in focal ischemic stroke caused by obstruction of a main cerebral artery in a human mammal which comprise the step of co-administering effective amounts of tissue plasminogen actiator (tPA) and ati-CD18 antibody to mammal wherein neither the tPA nor the anti-CD18 antibody is administered to the mammal until about three to five hours after the onset of focal ischmic stroke.

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