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Multi-sensor array for electrochemical recognition of nucleotide sequences and methods

  • US 20020081588A1
  • Filed: 12/21/2000
  • Published: 06/27/2002
  • Est. Priority Date: 06/24/1998
  • Status: Abandoned Application
First Claim
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1. A nucleic acid sensor for detecting target nucleic acid, the nucleic acid sensor comprising:

  • a) an electrode;

    b) redox polymer disposed on the electrode;

    c) enzyme disposed on the electrode; and

    d) a sensor nucleic acid coupled to the redox polymer, wherein, in the presence of a substrate, the enzyme generates a detection compound, and wherein binding of the sensor nucleic acid to the target nucleic acid results in an increased rate of oxidation or reduction of the detection compound.

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