Mechanical clot treatment device with distal filter

• US 20020082558A1
• Filed: 02/22/2002
• Published: 06/27/2002
• Est. Priority Date: 09/30/1997
• Status: Active Grant

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Inventors: Samson, Gene, Carrison, Harold F.
• Granted Patent: US 7,875,050 B2
• Time in Patent Office: Days
• US Class Current: 604/159
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22045 fixed to the catheter; guiding tip
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2090/376 using X-rays, e.g. fluoroscopy
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/0108 Both ends closed, i.e. legs gathered at both ends
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0071 spherical

Abstract

This is a surgical device usually delivered through an intravascular catheter. It may be used in several ways. It may, for instance, be used to open a clear passageway adjacent thrombus to allow both blood and medication to bypass the clot. It may be used to pierce and to remove thrombus. These thrombus are often found in tortuous vasculature. The device includes several sections. The device has a core element, typically a core wire. Placed around the distal end of the core element is a collapsible but preferably self expanding proximal cage assembly and a distal filter, preferably a self-expanding cage assembly or other filter component. The various portions of those components are preferably radio-opaque. The proximal end of the proximal cage is typically is affixed to an actuator in such a way as to allow expansion of the cage after deployment. The proximal cage assembly may be used for collecting emboli or for displacing them to allow blood flow to resume, either with or without concurrent clot-dissolving drug treatment. The distal sector, whether a self-expanding cage or fan, is placed distally of the thrombus to collect portions of the thrombus which may loosen during the treatment or removal procedure.

Claims

1. A removable flow restoration device comprising:

core element means having a distal portion for navigation to a therapeutic site in a lumen and for assisting in puncturing or displacing an occlusion,

a first filter means distally located on the core element means for collecting, displacing, or moving the occlusion,

a second filter means located on the core element means distal to the first filter means for placement distal to the occlusion to catch the occlusion or fragments thereof,

wherein the core element means passes through the first and second filter means, and

actuator means for expanding or collapsing the first and second filter means about the core element means.

2. The removable flow restoration device of claim 1 wherein the actuator means is electrolytically activated.

3. The removable flow restoration device of claim 1 wherein the actuator means is mechanically activated.

4. The removable flow restoration device of claim 1 additionally comprising a tip located on a distalmost end of the core element means.

5. The removable flow restoration device of claim 1 wherein a ratio of an outer diameter of the first filter means when expanded to an outer diameter of the first filter means when collapsed is between about 2 to 1 and 10 to 1.

6. The removable flow restoration device of claim 1 wherein a ratio of an outer diameter of the second filter means when expanded to an outer diameter of the second filter means when collapsed is between about 2 to 1 and 10 to 1.

7. The removable flow restoration device of claim 1 wherein the core element means is axially moveable within the first and second filter means.

8. The removable flow restoration device of claim 1 wherein the core element means is rotatable with respect to and non-removable from the first filter means.

9. A removable flow restoration device comprising:

a core element comprising at least an elongated core wire having a distal end and a proximal end,

a proximal cage located substantially coaxial about the core element through which the core element passes,

a separator located substantially coaxial about the core element and distal to the proximal cage,

a distal cage through which the core element passes, located substantially coaxial about the core element and distal to the separator element, the distal cage comprising a plurality of petal-shaped members, at least one of which has a distal rake,

wherein the core element passes through the first and second cages,

a tubular actuator for expanding and contracting the proximal and distal cages, located substantially coaxial about the core element and proximal to the proximal cage,and

a tip member located distal to the distal cage.

10. The removable flow restoration device of claim 9 wherein the proximal cage comprises a woven braid of ribbons.

11. The removable flow restoration device of claim 9 wherein at least a portion of the proximal cage comprises a superelastic alloy.

12. The removable flow restoration device of claim 9 wherein at least a portion of the petal-shaped members comprise wires.

13. The removable flow restoration device of claim 9 wherein at least a portion of the first cage or second cage is radio-opaque.

15. The embolism treatment device of claim 14 wherein the tubular liner is polymeric.

16. The embolism treatment device of claim 15 wherein the tubular liner comprises polytetrafluoroethylene.

17. The embolism treatment device of claim 14 additionally comprising a tubular member located substantially coaxial to the core element and distal to the distal cage for affixing a distal end of the distal cage to the tubular liner.

18. The embolism treatment device of claim 17 additionally comprising a radio-opaque marker affixed to the tubular member.

19. The embolism treatment device of claim 14 wherein a ratio of an outer diameter of the proximal cage when expanded to an outer diameter of the proximal cage when collapsed is between about 2 to 1 and 10 to 1.

20. The embolism treatment device of claim 14 wherein a ratio of an outer diameter of the distal cage when expanded to an outer diameter of the distal cage when collapsed is between about 2 to 1 and 10 to 1.

14. An embolism treatment device comprising:

a core element comprising at least an elongated core wire having a distal end and a proximal end,

a proximal cage located substantially coaxial about the core element through which the core element is axially movable,

a woven braided distal cage located substantially coaxial about the core element and distal to the proximal cage, through which the core element is axially movable within a tubular liner, and

an actuator for expanding and contracting the proximal and distal cages, located substantially coaxial about the core element and proximal to the proximal cage.