Micro-dialysis probe

• US 20020087145A1
• Filed: 02/05/2002
• Published: 07/04/2002
• Est. Priority Date: 08/06/1999
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Disetronic Licensing Ag
• Inventors: Ehwald, Rudolf, Thomas, Andreas, Uwe, Beyer
• Granted Patent: US 7,008,398 B2
• Time in Patent Office: Days
• US Class Current: 604/523
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14528 invasively

Abstract

The invention relates to a micro-dialysis probe which includes a supply line (1) and a drainage line (6) for a drip-feed solution and a dialysis section, wherein the flow channel for the drip-feed solution experiences an inversion in the area of the dialysis section between the supply line (1) and the drainage line (6), and wherein both the supply line (1) and the drainage line (6) are respectively arranged as separate hollow channels on the outer wall of the probe, side by side, in particular parallel.

Claims

1. A micro-dialysis probe which includes a supply line and a drainage line for a drip-feed solution and a dialysis section, wherein the flow channel for said drip-feed solution experiences an inversion in the area of said dialysis section between said supply line and said drainage line, characterised in that both said supply line and said drainage line are respectively arranged as separate hollow channels on the outer wall of said probe, side by side, in particular parallel.

2. The micro-dialysis probe as set forth in claim 1, characterised in that the first section of said drainage line in the direction of the flow consists of a dialysis hollow fiber penetrating into said supply line behind said inversion, said hollow fiber being fastened in the area of the sealed tip of said probe such that a linear course of flow is achieved after said inversion, while at its other end it is sealed into a second stable tube of the drainage line.

3. The micro-dialysis probe as set forth in claim 2, characterised in that the part of said tube in the area of said tip of said probe which lies over said hollow fiber forms a supporting section.

4. The micro-dialysis probe as set forth in claim 2, characterised in that said hollow fiber is formed to be replaceable and is sealed in, said tube and in particular said supporting section comprising recesses via which said hollow fiber is exposed outwards.

5. The micro-dialysis probe as set forth in claim 1, characterised in that the flow channel for said drip-feed solution consists of a hollow fiber with a supporting profile inserted into it, which separates said supply line and said drainage line from each other, said supporting profile comprising overflow openings in the area of flow inversion.

6. The micro-dialysis probe as set forth in claim 5, characterised in that said hollow fiber, at the supply line end and drainage line end of said probe is sealed into a probe shaft which accommodates and continues said supply line and said drainage line separately.

7. The micro-dialysis probe as set forth in claim 5, characterised in that said profile is formed star-shaped, in particular as a three- or four-armed star.

8. The micro-dialysis probe as set forth in claim 5, characterised in that said profile is formed flat.

9. The micro-dialysis probe as set forth in claim 8, characterised in that said profile comprises bristles or knobs on at least one of its flat sides, to support said hollow fiber.

10. The micro-dialysis probe as set forth in any one of claims 1 to 9, characterised in that said supply line and/or said drainage line have a substantially linear course.