Method and device for preventing contrast associated nephropathy

• US 20020091349A1
• Filed: 01/09/2001
• Published: 07/11/2002
• Est. Priority Date: 01/09/2001
• Status: Active Grant

• Current Assignee: Mount Sinai School of Medicine (Sinai Health System)
• Original Assignee: Mount Sinai School of Medicine of New York University
• Inventors: Reich, David
• Granted Patent: US 6,554,819 B2
• Time in Patent Office: Days
• US Class Current: 604/5.01
• CPC Class Codes: A61M 1/3653 Interfaces between patient blood circulation and extra-corporal blood circuit
• CPC Class Codes: A61M 1/3659 Cannulae pertaining to extracorporeal circulation
• CPC Class Codes: A61M 31/005 for contrast media

Abstract

A method and device for preventing contrast associated nephropathy are disclosed. When contrast solution is injected into the coronary artery of a patient, blood is prevented from flowing through the coronary sinus into the right atrium. The blood in the coronary sinus is bypassed to a filtration device which filters out the contrast solution from the blood and recirculates the blood back to the patient. Preferably, blood flow from the coronary sinus is blocked by a balloon catheter which includes a port distal of the balloon so that when the sinus is occluded, blood flows from the sinus into the central lumen of the catheter where it can be directed to the filtration device.

Claims

1. A method for preventing contrast associated nephropathy, comprising inserting a catheter into a patient'"'"'s coronary sinus, blocking blood flow from the coronary sinus into the right atrium, draining blood from the coronary sinus through the catheter while the blood flow is blocked, and removing contrast solution from the blood which passes through the catheter.

2. A method for preventing contrast associated nephropathy according to claim 1, wherein the blood is returned to the patient after the contrast solution has been removed.

3. A method for preventing contrast associated nephropathy according to claim 1, wherein blood flow is only blocked when the contrast solution is introduced into the patient.

4. A method for preventing contrast associated nephropathy, comprising inserting a balloon catheter into a patient'"'"'s coronary sinus, expanding the balloon to prevent blood flow from the coronary sinus to the right atrium, draining blood from the coronary sinus through the catheter while blood flow is blocked, filtering the blood from the catheter to remove contrast solution, and returning the filtered blood to the patient.

5. A method for preventing contrast associated nephropathy according to claim 4, wherein the balloon is only inflated when the contrast solution is introduced into the patient.

6. A catheter for use in preventing contrast associated nephropathy, comprising an elongated tubular shaft, deployable means on said tubular shaft for blocking the flow of blood from the coronary sinus to the right atrium, said catheter further including means for draining blood flow from the coronary sinus into the catheter whereby contrast solution in the blood can be removed.

7. A catheter according to claim 6, further including means on the catheter for retaining the catheter within the coronary sinus when the sinus is blocked.

8. A catheter for use in preventing contrast associated nephropathy, comprising an elongated tubular shaft, an inflatable balloon positioned in the distal portion of the catheter and adapted to block the flow of blood from the coronary sinus to the right atrium, and a port within the catheter shaft distal of the balloon for draining blood flow from the coronary sinus, whereby blood from the coronary sinus can be filtered to remove contrast solution.

9. A catheter according to claim 8, further including means distal of the balloon for retaining the catheter within the coronary sinus when the occlusion balloon is deflated.

10. A method for preventing contrast associated nephropathy, comprising inserting a catheter into a patient'"'"'s vein where there is a high concentration of a contrast solution, blocking blood flow from the vein to the patient'"'"'s kidney, draining blood from the vein through the catheter while the blood flow is blocked, and removing contrast solution from the blood which passes through the catheter.

11. A method for preventing contrast associated nephropathy according to claim 10, wherein the blood is returned to the patient after the contrast solution has been removed.

12. A method for preventing contrast associated nephropathy according to claim 10, wherein blood flow is only blocked when the contrast solution is introduced into the patient.